Matters Arising |
Featured
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Article |
Single-particle cryo-EM at atomic resolution
Advances in electron cryo-microscopy hardware allow proteins to be studied at atomic resolution.
- Takanori Nakane
- , Abhay Kotecha
- & Sjors H. W. Scheres
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Letter |
RETRACTED ARTICLE: Detection and replication of epistasis influencing transcription in humans
Epistasis has rarely been shown among natural polymorphisms in human traits; this research using advanced computation and gene expression data reveals many instances of epistasis between common single nucleotide polymorphisms in humans, with epistasis and the direction of its effect replicating in independent cohorts.
- Gibran Hemani
- , Konstantin Shakhbazov
- & Joseph E. Powell
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News & Views |
The fragility of interdependency
A study of failures in interconnected networks highlights the vulnerability of tightly coupled infrastructures and shows the need to consider mutually dependent network properties in designing resilient systems.
- Alessandro Vespignani