Naturally occurring cationic host defence peptides, also known as antimicrobial peptides, can control infections by their direct microbicidal properties and by modulating the host’s immune responses. In addition, certain cationic host defence peptides can resolve harmful inflammation. Here, Mookherjee et al. assess the emerging potential to therapeutically harness these peptides to treat infectious diseases, chronic inflammatory disorders and wound healing, highlighting current preclinical studies and clinical trials.
“Platelet-Rich Fibrin Membrane-as a novel biomaterial for pressure injury healing in a person with spinal cord injury: A case report”
Ascorbate maintains a low plasma oxygen level
Distribution of nerve fibers and nerve-immune cell association in mouse spleen revealed by immunofluorescent staining
T cell subsets and functions in atherosclerosis
Antimicrobial host defence peptides: functions and clinical potential
Genetic predisposition to mosaic Y chromosome loss in blood
Age-related loss of Y chromosome in leukocytes linked to cardiac fibrosis
T cell differentiation in Sjögren syndrome is regulated by TOX
The centuries long pursuit to map the human lymphatic system
HLA autoimmunity risk alleles influence T cell receptor sequences
proBDNF blockade modulates SLE
B cells: deplete, repopulate, vaccinate