Gonadal hormones articles within Nature

Featured

  • Letter |

    Progesterone stimulates an increase in Ca2+ levels in human sperm, but the underlying signalling mechanism is poorly understood. Two studies now show that progesterone activates the sperm-specific, pH-sensitive CatSper calcium channel, leading to a rapid influx of Ca2+ ions into the spermatozoa. These results should help to define the physiological role of progesterone and CatSper in sperm, and could lead to the development of new classes of non-hormonal contraceptives.

    • Polina V. Lishko
    • , Inna L. Botchkina
    •  & Yuriy Kirichok

  • Letter |

    Progesterone stimulates an increase in Ca2+ levels in human sperm, but the underlying signalling mechanism is poorly understood. Two studies now show that progesterone activates the sperm-specific, pH-sensitive CatSper calcium channel, leading to a rapid influx of Ca2+ ions into the spermatozoa. These results should help to define the physiological role of progesterone and CatSper in sperm, and could lead to the development of new classes of non-hormonal contraceptives.

    • Timo Strünker
    • , Normann Goodwin
    •  & U. Benjamin Kaupp

  • News & Views |

    Hormones are not all-powerful in determining whether birds develop with male or female features. Chickens that are genetic sexual mosaics reveal that individual cells also have a say in the matter.

    • Lindsey A. Barske
    •  & Blanche Capel

  • Authors |

    Testosterone's 'bad guy' image is rooted in folklore, not fact.

Browse broader subjects

Browse Gonadal hormones across other nature.com journals