Gastro-oesophageal reflux disease articles within Nature Communications

Featured

• Article
  19 February 2021 | Open Access

  GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

  Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.

  • Yeda Wu
  • , Graham K. Murray
  •  & Naomi R. Wray

• Article
  16 September 2019 | Open Access

  Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases

  Gastroesophageal reflux disease (GERD) is a major risk factor for Barret’s esophagus (BE) and esophageal adenocarcinoma (EA). Here, An et al. report 25 genetic loci for GERD, many of which associate with BE and EA or with other traits such as BMI.

  • Jiyuan An
  • , Puya Gharahkhani
  •  & Stuart MacGregor