Featured
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Article |
Establishment of fetomaternal tolerance through glycan-mediated B cell suppression
Pathways of glycan-mediated B cell suppression during pregnancy are important for promoting fetomaternal tolerance.
- G. Rizzuto
- , J. F. Brooks
- & A. Erlebacher
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Article |
Human germinal centres engage memory and naive B cells after influenza vaccination
The human germinal centre response to influenza virus vaccination is fuelled by the continued recruitment of naive B cells as well as pre-existing memory B cells.
- Jackson S. Turner
- , Julian Q. Zhou
- & Ali H. Ellebedy
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Letter |
Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
Hypoxia in germinal centres regulates B cell class switching via its effects on mTOR complex 1 and activation-induced cytosine deaminase activity.
- Sung Hoon Cho
- , Ariel L. Raybuck
- & Mark R. Boothby
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Letter |
Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress
Lymphocyte migration in the spleen is visualized live in mice using a real-time two-photon laser-scanning microscopy approach revealing that marginal zone and follicular B cells are highly motile and can shuttle between compartments, and integrin adhesion is the key to cellular retention in the marginal zone.
- Tal I. Arnon
- , Robert M. Horton
- & Jason G. Cyster