Endocrine cancer articles within Nature Medicine

Featured

• Article | 10 February 2020

  Using human genetics to understand the disease impacts of testosterone in men and women

  Genetic analysis of data from over 400,000 participants in the UK Biobank Study shows that circulating testosterone levels have sex-specific implications for cardiometabolic diseases and cancer outcomes.

  • Katherine S Ruth
  • , Felix R Day
  •  & John R. B. Perry

• Perspective | 06 June 2017

  Biology and evolution of poorly differentiated neuroendocrine tumors

  Rubin and colleagues discuss the origin and evolution of poorly differentiated neuroendocrine tumors, and highlight potential new therapeutic strategies.

  • David S Rickman
  • , Himisha Beltran
  •  & Mark A Rubin

• Letter | 09 February 2015

  A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease

  Inhibition of Hsp90 as its C-terminus allows for the mature folding of GR and its full activity, thus ameliorating Cushing symptoms in a mouse model.

  • Mathias Riebold
  • , Christian Kozany
  •  & Marcelo Paez-Pereda