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| Open AccessFirst-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants
- Allison Titong
- , Sachith Gallolu Kankanamalage
- & Yue Liu
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| Open AccessDasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice
- Hidetaka Ota
- & Ayuto Kodama
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| Open AccessSynthetic antibacterial minerals: harnessing a natural geochemical reaction to combat antibiotic resistance
- Keith D. Morrison
- , Kelly A. Martin
- & Gabriela G. Loots
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| Open AccessStudy on the effect of koumiss on the intestinal microbiota of mice infected with Toxoplasma gondii
- Xinlei Yan
- , Wenying Han
- & Jun Guo
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| Open AccessIntegration of a miniaturized DMMB assay with high-throughput screening for identifying regulators of proteoglycan metabolism
- Yi Sun
- , Yuen-kee Tsui
- & Victor Leung
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| Open AccessNeuropsychopharmacological profiling of scoparone in mice
- Joanna Kowalczyk
- , Barbara Budzyńska
- & Krystyna Skalicka-Woźniak
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| Open AccessInterrelationship between 2019-nCov receptor DPP4 and diabetes mellitus targets based on protein interaction network
- Qian Gao
- , Wenjun Zhang
- & Huawei Jin
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| Open AccessAmikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility
- Jesus Magallon
- , Peter Vu
- & Marcelo E. Tolmasky
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| Open AccessModulation of oxidative and nitrosative stress attenuates microvascular hyperpermeability in ovine model of Pseudomonas aeruginosa sepsis
- Satoshi Fukuda
- , Yosuke Niimi
- & Perenlei Enkhbaatar
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| Open AccessIn vivo biocompatibility evaluation of in situ-forming polyethylene glycol-collagen hydrogels in corneal defects
- Yoon Hong Chun
- , Sun-Kyoung Park
- & Kyung-Sun Na
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| Open AccessFactor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules
- Patrick Stoiber
- , Pietro Scribani Rossi
- & Ulla Hansen
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| Open AccessDrug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence
- Kanglin Hsieh
- , Yinyin Wang
- & Yejin Kim
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| Open AccessPharmacokinetic and pharmacodynamic similarity between SAR341402 insulin aspart and Japan-approved NovoRapid in healthy Japanese subjects
- Masanari Shiramoto
- , Tatsuya Yoshihara
- & Hideya Muto
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| Open AccessA pan-cancer analysis revealing the role of TIGIT in tumor microenvironment
- Jie Wen
- , Xueyi Mao
- & Fangkun Liu
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| Open AccessResuscitative efficacy of hemoglobin vesicles for severe postpartum hemorrhage in pregnant rabbits
- Hiroki Ishibashi
- , Kohsuke Hagisawa
- & Masashi Takano
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| Open AccessInteraction of Spike protein and lipid membrane of SARS-CoV-2 with Ursodeoxycholic acid, an in-silico analysis
- Francisco Javier Rodal Canales
- , Laura Pérez-Campos Mayoral
- & Eduardo Pérez-Campos
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| Open AccessDevelopment of a rat capnoperitoneum phantom to study drug aerosol deposition in the context of anticancer research on peritoneal carcinomatosis
- Daniel Göhler
- , Antje Geldner
- & Urs Giger-Pabst
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| Open AccessImproving the self-assembly of bioresponsive nanocarriers by engineering doped nanocarbons: a computational atomistic insight
- Mohammad Khedri
- , Nima Beheshtizadeh
- & Sima Rezvantalab
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| Open AccessInferring a causal relationship between ceramide levels and COVID-19 respiratory distress
- Mehran M. Khodadoust
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| Open AccessLong-term stability predictions of therapeutic monoclonal antibodies in solution using Arrhenius-based kinetics
- Drago Kuzman
- , Marko Bunc
- & Matjaž Bončina
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| Open AccessAnthrahydroquinone-2-6-disulfonate is a novel, powerful antidote for paraquat poisoning
- Jin Qian
- , Chun-Yuan Wu
- & Xiao-Ran Liu
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| Open AccessEnhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens
- Ditte E. Jæhger
- , Mie L. Hübbe
- & Thomas L. Andresen
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| Open AccessTheoretical and experimental study of interaction of macroheterocyclic compounds with ORF3a of SARS-CoV-2
- Natalia Sh. Lebedeva
- , Yury A. Gubarev
- & Oskar I. Koifman
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| Open AccessTanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway
- Huayuan Liu
- , Caiyun Liu
- & Guangjun Shi
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| Open AccessDihydroergotamine and triptan use to treat migraine during pregnancy and the risk of adverse pregnancy outcomes
- Anick Bérard
- , Shannon Strom
- & Detlef Albrecht
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| Open AccessTrimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control
- Wenliang Zhang
- , Baiyang You
- & Suixin Liu
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| Open AccessProlyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target
- Takeshi Yamamotoya
- , Yusuke Nakatsu
- & Takemasa Sakaguchi
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| Open AccessApplication of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models
- Megan C. Cox
- , Rita Mendes
- & Catarina Brito
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| Open AccessTreatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitor
- Maja Zakošek Pipan
- , Sonja Prpar Mihevc
- & Gregor Majdič
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| Open AccessThe tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer
- Dianne J. Beveridge
- , Kirsty L. Richardson
- & Peter J. Leedman
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| Open AccessReveals of candidate active ingredients in Justicia and its anti-thrombotic action of mechanism based on network pharmacology approach and experimental validation
- Zongchao Hong
- , Ting Zhang
- & Bo Liu
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| Open AccessLOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling
- Caixia Zhang
- , Mengjiao Zhu
- & Huang Li
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| Open AccessThe GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS
- Amy Keerie
- , Heledd Brown-Wright
- & Richard J. Mead
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| Open AccessDipeptidyl peptidase-4 inhibitor cardiovascular safety in patients with type 2 diabetes, with cardiovascular and renal disease: a retrospective cohort study
- Sheriza Baksh
- , Jiajun Wen
- & G. Caleb Alexander
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| Open AccessRelative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study
- N. Boqué
- , R. M. Valls
- & R. Solà
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| Open AccessA KLK4 proteinase substrate capture approach to antagonize PAR1
- Eitan Rabinovitch
- , Koishiro Mihara
- & Niv Papo
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| Open AccessTargeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases
- Marialuisa Moccia
- , Donglin Yang
- & Francesca Carlomagno
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| Open AccessEradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries
- Hung-Ju Hsu
- , Chao-Ping Tung
- & An-Suei Yang
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| Open AccessGlutamic acid promotes hair growth in mice
- Carlos Poblete Jara
- , Beatriz de Andrade Berti
- & Eliana Pereira Araújo
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| Open AccessThe recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters
- Cleide Oliveira
- , Mayara Vioto Valois
- & Francisco Humberto de Abreu Maffei
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| Open AccessInsights into antioxidant activities and anti-skin-aging potential of callus extract from Centella asiatica (L.)
- Visarut Buranasudja
- , Dolly Rani
- & Sornkanok Vimolmangkang
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| Open AccessRecovery of high specific activity molybdenum-99 from accelerator-induced fission on low-enriched uranium for technetium-99m generators
- M. Alex Brown
- , Nathan Johnson
- & Peter Tkac
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| Open AccessValidity and safety of ID-JPL934 in lower gastrointestinal symptom improvement
- Cheol Min Shin
- , Yoon Jin Choi
- & Nayoung Kim
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| Open AccessCombination of 131I-trastuzumab and lanatoside C enhanced therapeutic efficacy in HER2 positive tumor model
- Nagarajan Vinod
- , Jae Hyung Kim
- & Ilhan Lim
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| Open AccessLysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse
- Long T. Nguyen
- , Sonia Saad
- & Carol A. Pollock
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| Open AccessInvestigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain
- Lumeng J. Yu
- , Victoria H. Ko
- & Mark Puder
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| Open AccessComparison of different anesthesia modalities during percutaneous kyphoplasty of osteoporotic vertebral compression fractures
- Chaoyuan Ge
- , Xucai Wu
- & Liang Dong
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| Open AccessSmall molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers
- Martina Meßner
- , Melanie M. Mandl
- & Johanna Pachmayr