DNA nanotechnology

DNA nanotechnology is a branch of nanotechnology concerned with the design, study and application of synthetic structures based on DNA. DNA nanotechnology takes advantage of the physical and chemical properties of DNA rather than the genetic information it carries.

Latest Research and Reviews

  • Research | | open

    The creation of protective barriers around cells is of interest for a range of applications. Here, the authors report on the creation of DNA templated alginate-polylysine biomimetic cell walls for encapsulating and shielding cells, demonstrating protection against physical assaults and immune reactions.

    • Peng Shi
    • , Nan Zhao
    • , James Coyne
    •  & Yong Wang
  • Reviews |

    Throughout evolution, DNA has been the primary medium of biological information storage. In this article, Ceze, Nivala and Strauss discuss how DNA can be adopted as a storage medium for custom data, as a potential future complement to current data storage media such as computer hard disks, optical disks and tape. They discuss strategies for coding, decoding and error correction and give examples of implementation both in vitro and in vivo.

    • Luis Ceze
    • , Jeff Nivala
    •  & Karin Strauss
  • Research |

    Nucleic acid nanotechnology offers a promising route towards the design and synthesis of reconfigurable biomolecular materials. Now, the combination of dynamic and structural DNA nanotechnology has enabled the dynamic control of the assembly and disassembly of DNA nanotubes. The process involves minimal synthetic gene systems, including an autonomous molecular oscillator.

    • Leopold N. Green
    • , Hari K. K. Subramanian
    • , Vahid Mardanlou
    • , Jongmin Kim
    • , Rizal F. Hariadi
    •  & Elisa Franco
  • Research | | open

    Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.

    • Stefano Stassi
    • , Monica Marini
    • , Marco Allione
    • , Sergei Lopatin
    • , Domenico Marson
    • , Erik Laurini
    • , Sabrina Pricl
    • , Candido Fabrizio Pirri
    • , Carlo Ricciardi
    •  & Enzo Di Fabrizio

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