Cytological techniques

Cytological techniques are methods used in the study or manipulation of cells. These include methods used in cell biology to culture, track, phenotype, sort and screen cells in populations or tissues, and molecular methods to understand cellular function.

Latest Research and Reviews

Research
21 December 2022 | Open Access

Dicentric chromosome assay using a deep learning-based automated system
- Soo Kyung Jeong
- , Su Jung Oh
- & Wol Soon Jo
Scientific Reports 12, 22097
Research
20 December 2022 | Open Access

Direct detection of circulating donor-derived extracellular vesicles in kidney transplant recipients
- Wouter W. Woud
- , Dennis A. Hesselink
- & Karin Boer
Scientific Reports 12, 21973
Research
09 December 2022 | Open Access

An efficient human stem cells derived cardiotoxicity testing platform for testing oncotherapeutic analogues of quercetin and cinnamic acid
- Saurabh Mandal
- , Naisarg Gamit
- & Sudha Warrier
Scientific Reports 12, 21362
Research
25 November 2022 | Open Access

Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples

The association of specific immune cell types with SARS-CoV-2 severity is not fully understood. Here the authors analyse PBMC from individuals recovered from COVID-19 and propose immune cell signatures post recovery that are associated with disease severity.
- Thomas Liechti
- , Yaser Iftikhar
- & Mario Roederer
Nature Communications 13, 7255
Reviews | 03 November 2022

Imaging flow cytometry

Imaging flow cytometry combines the high-event-rate nature of flow cytometry with single-cell image acquisition associated with microscopy. In this Primer, Rees et al. discuss the typical imaging flow instrumentation, the type of data acquired and how to analyse them.
- Paul Rees
- , Huw D. Summers
- & Minh Doan
Nature Reviews Methods Primers 2, 86
Research
21 October 2022 | Open Access

Automated classification of estrous stage in rodents using deep learning
- Nora S. Wolcott
- , Kevin K. Sit
- & Michael J. Goard
Scientific Reports 12, 17685

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News and Comment

Research Highlights | 21 November 2022

Assigning phenotypes to essential human genes

A microscopy-based pooled CRISPR screening approach described in Cell enables the cellular functions of thousands of genes to be assessed at remarkable phenotypic depth.
- Dorothy Clyde
Nature Reviews Genetics 24, 2
Research Highlights | 04 November 2022

Broken hierarchies
- Ioana Visan
Nature Immunology 23, 1520
Research Highlights | 10 June 2022

Modeling multi-organ systems on a chip

To recapitulate some of the complexities of the human physiology, engineered tissues can be linked by vascular flow in a multi-organ chip.
- Nina Vogt
Nature Methods 19, 641
Correspondence | 04 May 2022

Best practices for reporting throughput in biomedical research
- Maik Herbig
- , Akihiro Isozaki
- & Keisuke Goda
Nature Methods 19, 633-634
Editorial | 11 March 2022

Catching up with multiplexed tissue imaging

Highly multiplexed tissue imaging continues to show its power for biomedical discovery. In this issue, we publish tools and guidance for implementing this class of methods and reporting subsequent results.

Nature Methods 19, 259
Research Highlights | 11 January 2022

Recapitulating miRNA biogenesis in cells

MapToCleave enables the large-scale study of miRNA precursor processing in living cells.
- Lei Tang
Nature Methods 19, 35

All News & Comment

Cytological techniques

Latest Research and Reviews

Dicentric chromosome assay using a deep learning-based automated system

Direct detection of circulating donor-derived extracellular vesicles in kidney transplant recipients

An efficient human stem cells derived cardiotoxicity testing platform for testing oncotherapeutic analogues of quercetin and cinnamic acid

Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples

Imaging flow cytometry

Automated classification of estrous stage in rodents using deep learning

News and Comment

Assigning phenotypes to essential human genes

Broken hierarchies

Modeling multi-organ systems on a chip

Best practices for reporting throughput in biomedical research

Catching up with multiplexed tissue imaging

Recapitulating miRNA biogenesis in cells

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