Chemoprevention articles within Nature Communications

Featured

• Article
  29 January 2019 | Open Access

  Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children

  Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al. evaluate the use of dihydroartemisinin-piperaquine as a regimen in 179 children, and population-based simulations suggest that small children would benefit from a higher and extended dosage.

  • Palang Chotsiri
  • , Issaka Zongo
  •  & Joel Tarning

• Article
  06 June 2012 | Open Access

  Estimating the potential public health impact of seasonal malaria chemoprevention in African children

  Seasonal malaria chemoprevention can lower the incidence of malaria in areas where transmission is highly periodical. Combining data on rainfall, population and malaria endemicity, Cairnset al. identify geographical areas in sub-Saharan Africa where this intervention is likely to be effective and cost-effective.

  • Matthew Cairns
  • , Arantxa Roca-Feltrer
  •  & Brian M. Greenwood