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| Open AccessGlucocorticoid stress hormones stimulate vesicle-free Tau secretion and spreading in the brain
- Qing Yu
- , Fang Du
- & Clarissa L. Waites
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| Open AccessScreens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease
- Meng-Lu Liu
- , Shuaipeng Ma
- & Chun-Li Zhang
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| Open AccessLocal production of reactive oxygen species drives vincristine-induced axon degeneration
- Jorge Gomez-Deza
- , Anastasia L. Slavutsky
- & Claire E. Le Pichon
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| Open AccessTunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
- Ranabir Chakraborty
- , Takashi Nonaka
- & Chiara Zurzolo
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| Open AccessMultiple sclerosis plasma IgG aggregates induce complement-dependent neuronal apoptosis
- Wenbo Zhou
- , Michael Graner
- & Xiaoli Yu
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| Open AccessDying transplanted neural stem cells mediate survival bystander effects in the injured brain
- Wei Han
- , Eva-Maria Meißner
- & Carsten Culmsee
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| Open AccessModulations of the neuronal trafficking of tissue-type plasminogen activator (tPA) influences glutamate release
- Alexandre Varangot
- , Simon Lebatard
- & Denis Vivien
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| Open AccessAstrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
- Yang Deng
- , Rui Duan
- & Junrong Zhu
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| Open AccessCrosstalk of Synapsin1 palmitoylation and phosphorylation controls the dynamicity of synaptic vesicles in neurons
- Peipei Yan
- , Huicong Liu
- & Eryan Kong
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| Open AccessATM rules neurodevelopment and glutamatergic transmission in the hippocampus but not in the cortex
- Elisa Focchi
- , Clara Cambria
- & Flavia Antonucci
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| Open AccessBimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
- Elena R. Rhymes
- , Andrew P. Tosolini
- & Giampietro Schiavo
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| Open AccessAgeing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment
- Manman Zhang
- , Wenliang Gong
- & Baoman Li
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| Open AccessVDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway
- Erica de Sousa
- , Marília Inês Móvio
- & Alexandre Hiroaki Kihara
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| Open AccessRAGE-TXNIP axis drives inflammation in Alzheimer’s by targeting Aβ to mitochondria in microglia
- Oualid Sbai
- , Mehdi Djelloul
- & L. Perrone
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| Open AccessRab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production
- Viktoriya Zhuravleva
- , João Vaz-Silva
- & Clarissa L. Waites
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| Open AccessExtracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway
- Lin Zhang
- , Wei Wei
- & Thorsten R. Doeppner
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| Open AccessVezatin regulates seizures by controlling AMPAR-mediated synaptic activity
- You Wang
- , Jinxian Yuan
- & Tao Xu
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| Open AccessGenetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia
- Olga Kopach
- , Noemí Esteras
- & Dmitri A. Rusakov
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| Open AccessThe hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke
- Valeria Valsecchi
- , Giusy Laudati
- & Giuseppe Pignataro
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| Open AccessAn interaction between PRRT2 and Na+/K+ ATPase contributes to the control of neuronal excitability
- Bruno Sterlini
- , Alessandra Romei
- & Anna Corradi
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| Open AccessCaspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits
- Anastasia Noël
- , Bénédicte Foveau
- & Andréa C. LeBlanc
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| Open AccessTargeted de-repression of neuronal Nrf2 inhibits α-synuclein accumulation
- Paul S. Baxter
- , Nóra M. Márkus
- & Giles E. Hardingham
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| Open AccessNeuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF
- Federica Buffolo
- , Valentina Petrosino
- & Fabio Benfenati
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| Open AccessSirtuin 1-dependent regulation of high mobility box 1 in hypoxia–reoxygenated brain microvascular endothelial cells: roles in neuronal amyloidogenesis
- Young-Sun Lee
- , Ji-Young Choi
- & Ju-Hee Kang
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| Open Access(D620N) VPS35 causes the impairment of Wnt/β-catenin signaling cascade and mitochondrial dysfunction in a PARK17 knockin mouse model
- Ching-Chi Chiu
- , Yi-Hsin Weng
- & Hung-Li Wang
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| Open AccessAmitriptyline interferes with autophagy-mediated clearance of protein aggregates via inhibiting autophagosome maturation in neuronal cells
- Yoonjung Kwon
- , Yeojin Bang
- & Hyun Jin Choi
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Article
| Open AccessNLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease
- Xiao-fei He
- , Jing-hui Xu
- & Xi-quan Hu
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Article
| Open AccessPersistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain
- Xiaqing Ma
- , Wenjie Du
- & Tao Xu
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| Open AccessProteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice
- Giulia Dematteis
- , Gabrielė Vydmantaitė
- & Laura Tapella
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| Open AccessTMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities
- Zhaoji Liu
- , Jinhuan Ning
- & Yun-wu Zhang
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Article
| Open AccessMaf1 regulates dendritic morphogenesis and influences learning and memory
- Kui Chen
- , Liang Zhu
- & Dong-Fu Feng
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| Open AccessNMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion
- Guangyun Wang
- , Tiezheng Wang
- & Junping Kou
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| Open AccessInternalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies
- Nicha Puangmalai
- , Nemil Bhatt
- & Rakez Kayed
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| Open AccessCaloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus
- Alexander Popov
- , Pavel Denisov
- & Alexey Semyanov
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Article
| Open AccessBeta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling
- Claire S. Durrant
- , Karsten Ruscher
- & Ilknur Özen
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| Open AccessThe orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor
- Sarah M. Estrada
- , Andrew S. Thagard
- & Nicholas Ieronimakis
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Article
| Open AccessAutoantibodies to synapsin I sequestrate synapsin I and alter synaptic function
- Anna Rocchi
- , Silvio Sacchetti
- & Fabio Benfenati
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Article
| Open AccessMitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
- Goutham K. Ganjam
- , Kathrin Bolte
- & Carsten Culmsee
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| Open AccessERβ promotes Aβ degradation via the modulation of autophagy
- Yong Wei
- , Jiawei Zhou
- & Jian Huang
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Article
| Open AccessF-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects
- Xiyue Cheng
- , Pei Pei
- & Ting Zhang
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Article
| Open AccessExcitotoxic targeting of Kidins220 to the Golgi apparatus precedes calpain cleavage of Rap1-activation complexes
- Celia López-Menéndez
- , Ana Simón-García
- & Teresa Iglesias
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Article
| Open AccessAβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling
- Tania Quintela-López
- , Carolina Ortiz-Sanz
- & Elena Alberdi
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Article
| Open AccessSuppressing the Na+/H+ exchanger 1: a new sight to treat depression
- Xueyang Deng
- , Zhouye Ji
- & Shiping Ma
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| Open AccessDynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis
- Yossi Buskila
- , Orsolya Kékesi
- & Lezanne Ooi
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Article
| Open AccessLRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation
- Marthe H. R. Ludtmann
- , Marko Kostic
- & Andrey Y. Abramov
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Article
| Open AccessNeuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
- Manon Domise
- , Florent Sauvé
- & Valérie Vingtdeux
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Article
| Open AccessTargeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1G93A Model
- Ariel Ionescu
- , Tal Gradus
- & Eran Perlson
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Article
| Open AccessPigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2
- Vasanthy Vigneswara
- & Zubair Ahmed
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| Open AccessSelective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicity
- Guendalina Bastioli
- , Silvia Piccirillo
- & Paolo Calabresi