Cellular imaging articles within Nature Communications

Featured

• Article
  29 May 2014 | Open Access

  Separating NADH and NADPH fluorescence in live cells and tissues using FLIM

  NAD and NADP play fundamentally different roles in cellular metabolism, and yet these pyridine nucleotides cannot be distinguished spectroscopically in living cells. Blacker et al.demonstrate that fluorescence lifetime imaging can be used to quantify NADPH/NADH balance in cultured cells and in the mammalian cochlea.

  • Thomas S. Blacker
  • , Zoe F. Mann
  •  & Michael R. Duchen

• Article
  25 September 2012 | Open Access

  Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle

  Current methods for detecting proliferation in live cells cannot distinguish between dividing cells and cells that are progressing through the cell cycle. Here, a method is described that detects anillin in the contractile ring and in the midbody of cells during M-phase, providing a more accurate detection of dividing cells.

  • Michael Hesse
  • , Alexandra Raulf
  •  & Bernd K. Fleischmann

• Article | 28 February 2012

  Three-dimensional imaging of single nanotube molecule endocytosis on plasmonic substrates

  Imaging and tracking the motion of single molecules on cell plasma membranes requires high spatial resolution in three dimensions. Honget al. develop a plasmonic ruler based on the fluorescence enhancement of carbon nanotubes on a gold plasmonic substrate, allowing the observation of nanotube endocytosis in three dimensions.

  • Guosong Hong
  • , Justin Z. Wu
  •  & Hongjie Dai