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| Open AccessLoss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy
- Mi-Gi Lee
- , Min-Ah Choi
- & Bum-Ho Bin
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| Open AccessThe Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
- Lei Bao
- , Fernanda Festa
- & Barbara A. Miller
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| Open AccessFatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway
- Hui-Yen Chuang
- , Yen-Po Lee
- & Jeng-Jong Hwang
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| Open AccessALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
- Tomaš Pilžys
- , Michał Marcinkowski
- & Elżbieta Grzesiuk
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| Open AccessPatched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1+/−/ODC transgenic mice
- Changzhao Li
- , Bharat Mishra
- & Mohammad Athar
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| Open AccessPulsed-wave Ultrasound Hyperthermia Enhanced Nanodrug Delivery Combined with Chloroquine Exerts Effective Antitumor Response and Postpones Recurrence
- Chi-Feng Chiang
- , Yu-Hone Hsu
- & Win-Li Lin
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| Open AccessEarly changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy
- Kazuki Ohya
- , Tomokazu Kawaoka
- & Hiroshi Aikata
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| Open AccessRadio-selective effects of a natural occurring muscle-derived dipeptide in A549 and normal cell lines
- Norma Ybarra
- & Jan Seuntjens
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| Open AccessIdentification of alkaline pH optimum of human glucokinase because of ATP-mediated bias correction in outcomes of enzyme assays
- Daniela Šimčíková
- & Petr Heneberg
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| Open AccessSpatial Regulation of Mitochondrial Heterogeneity by Stromal Confinement in Micropatterned Tumor Models
- Hydari Masuma Begum
- , Hoang P. Ta
- & Keyue Shen
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| Open AccessBruton’s tyrosine kinase is at the crossroads of metabolic adaptation in primary malignant human lymphocytes
- Bahram Sharif-Askari
- , Daniel Doyon
- & Raquel Aloyz
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| Open AccessPI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival
- Georgios Batsios
- , Pavithra Viswanath
- & Sabrina M. Ronen
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| Open AccessTissue amino acid profiles are characteristic of tumor type, malignant phenotype, and tumor progression in pancreatic tumors
- Nobuyoshi Hiraoka
- , Sakino Toue
- & Kazuaki Shimada
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| Open AccessComprehensive Metabolomic Analysis of IDH1R132H Clinical Glioma Samples Reveals Suppression of β-oxidation Due to Carnitine Deficiency
- Satsuki Miyata
- , Kaoru Tominaga
- & Hitoshi Endo
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| Open AccessDelayed recruiting of TPD52 to lipid droplets – evidence for a “second wave” of lipid droplet-associated proteins that respond to altered lipid storage induced by Brefeldin A treatment
- Yuyan Chen
- , Sarah Frost
- & Jennifer A. Byrne
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| Open AccessAssessment of 213Bi-anti-EGFR MAb treatment efficacy in malignant cancer cells with [1-13C]pyruvate and [18F]FDG
- Benedikt Feuerecker
- , Michael Michalik
- & Christof Seidl
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| Open AccessInterplay of fibroblasts with anaplastic tumor cells promotes follicular thyroid cancer progression
- Laura Fozzatti
- , Vanina Alejandra Alamino
- & Claudia Gabriela Pellizas
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| Open AccessDegradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations
- Raffaela S. Berger
- , Lisa Ellmann
- & Katja Dettmer
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| Open AccessLoss of PKM2 in Lgr5+ intestinal stem cells promotes colitis-associated colorectal cancer
- Yeji Kim
- , Yong-Soo Lee
- & Mi-Na Kweon
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| Open AccessMutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6
- Agnieszka Chryplewicz
- , Samantha M. Tienda
- & Mark A. Eckert
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| Open AccessAnti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation
- Quentin Spillier
- , Didier Vertommen
- & Raphaël Frédérick
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| Open AccessDual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells
- Shu Lian
- , Ruizhi Xie
- & Lee Jia
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| Open AccessA Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death
- Eun-Yeong Kim
- , Tae-Wook Chung
- & Ki-Tae Ha
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| Open AccessDynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization
- Jeffrey R. Brender
- , Shun Kishimoto
- & Murali C. Krishna
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| Open AccessMetabolic therapies inhibit tumor growth in vivo and in silico
- Jorgelindo da Veiga Moreira
- , Minoo Hamraz
- & Sabine Peres
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| Open AccessG6Pase location in the endoplasmic reticulum: Implications on compartmental analysis of FDG uptake in cancer cells
- Mara Scussolini
- , Matteo Bauckneht
- & Cecilia Marini
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| Open AccessReflection of treatment proficiency of hydroxyurea treated β-thalassemia serum samples through nuclear magnetic resonance based metabonomics
- Ayesha Khalid
- , Amna Jabbar Siddiqui
- & Syed Ghulam Musharraf
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| Open AccessmiR-148a regulates expression of the transferrin receptor 1 in hepatocellular carcinoma
- Kamesh R. Babu
- & Martina U. Muckenthaler
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| Open AccessCadaverine, a metabolite of the microbiome, reduces breast cancer aggressiveness through trace amino acid receptors
- Tünde Kovács
- , Edit Mikó
- & Péter Bai
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| Open AccessLabel-free Quantitative Analysis of Protein Expression Alterations in miR-26a-Knockout HeLa Cells using SWATH-MS Technology
- Hexiao Shen
- , Li Li
- & Lixin Ma
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| Open AccessIn vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma
- Eul Hyun Suh
- , Edward P. Hackett
- & Jae Mo Park
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| Open AccessToll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival in Cancer Cachexia Syndrome
- Felipe Henriques
- , Magno A. Lopes
- & Miguel L. Batista Jr.
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| Open AccessInactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis
- Patricia Santofimia-Castaño
- , Wenjun Lan
- & Juan Iovanna
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| Open AccessComprehensive Analysis of Gene Expression Profiles and DNA Methylome reveals Oas1, Ppie, Polr2g as Pathogenic Target Genes of Gestational Diabetes Mellitus
- Yan Zhang
- , Tiancheng Zhang
- & Yunyan Chen
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| Open AccessIn-vitro evaluation of apoptotic effect of OEO and thymol in 2D and 3D cell cultures and the study of their interaction mode with DNA
- Tahereh Jamali
- , Gholamreza Kavoosi
- & Susan K. Ardestani
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| Open AccessTargeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC
- Soohyun Lee
- , Jae-Seon Lee
- & Soo-Youl Kim
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| Open AccessGCSH antisense regulation determines breast cancer cells’ viability
- Anna Adamus
- , Petra Müller
- & Nadja Engel
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| Open AccessEffect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin
- Kavindra Nath
- , Jeffrey Roman
- & Jerry D. Glickson
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| Open AccessShikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis
- Xiaoyue Zhao
- , Yanan Zhu
- & Ke Zen
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| Open AccessMalic Enzyme 1 (ME1) is pro-oncogenic in ApcMin/+ mice
- Lorenzo M. Fernandes
- , Ahmed Al-Dwairi
- & Frank A. Simmen
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| Open AccessInvestigation of Novel Regulation of N-myristoyltransferase by Mammalian Target of Rapamycin in Breast Cancer Cells
- Marine Jacquier
- , Shiby Kuriakose
- & Shailly Varma Shrivastav
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| Open AccessNa/K-ATPase Y260 Phosphorylation–mediated Src Regulation in Control of Aerobic Glycolysis and Tumor Growth
- Moumita Banerjee
- , Xiaoyu Cui
- & Zijian Xie
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| Open AccessSensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes
- Constantinos Alexandrou
- , Saif Sattar Al-Aqbi
- & Alessandro Rufini
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| Open AccessCoordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics
- Jurgen Kriel
- , Kristian Müller-Nedebock
- & Ben Loos
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| Open AccessGlucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells
- Hitoshi Endo
- , Satoshi Owada
- & Masayuki Tatemichi
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| Open Access1-Methyl-D-tryptophan Reduces Tumor CD133+ cells, Wnt/β-catenin and NF-κβp65 while Enhances Lymphocytes NF-κβ2, STAT3, and STAT4 Pathways in Murine Pancreatic Adenocarcinoma
- Murad Alahdal
- , Yun Xing
- & Jin Liang
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| Open AccessCysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity
- Sofia C. Nunes
- , Cristiano Ramos
- & Jacinta Serpa
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| Open AccessAlterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations
- Raphaela Fritsche-Guenther
- , Christin Zasada
- & Stefan Kempa
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| Open AccessA Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- David E. Lee
- , Kinan Alhallak
- & Narasimhan Rajaram