Cajal bodies articles within Nature Communications

Featured

• Article
  15 November 2023 | Open Access

  Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

  DNA damage causes a major reorganization of the nucleolus. Here, the authors find that this structural restoration depends on the shuttling of the protein SMN from the Cajal bodies to the nucleolus, which requires coilin and PRMT1.

  • Shaqraa Musawi
  • , Lise-Marie Donnio
  •  & Giuseppina Giglia-Mari

• Article
  21 March 2016 | Open Access

  Cajal bodies are linked to genome conformation

  Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.

  • Qiuyan Wang
  • , Iain A. Sawyer
  •  & Miroslav Dundr