Bone marrow articles within Nature

Featured

  • Outlook |

    In the fight against myeloma, researchers are investigating its interactions with molecular neighbours in the bone marrow.

    • Virginia Hughes

  • Article |

    The identity of the cells that form the haematopoietic stem cell (HSC) niche in bone marrow has been unclear. These authors identify nestin-expressing mesenchymal stem cells as niche-forming cells. These nestin-expressing cells show a close physical association with HSCs and express high levels of genes involved in HSC maintenance, and their depletion reduces bone marrow homing of haematopoietic progenitors.

    • Simón Méndez-Ferrer
    • , Tatyana V. Michurina
    •  & Paul S. Frenette

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