Research Highlights |
Featured
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Research Highlights |
Our choice from the recent literature
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Article |
A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways
A photoactivatable nanoliposome carrying multikinase inhibitors tackles tumours by killing cancer cells through photodynamic therapy and simultaneously shutting down signalling pathways that allow cancerous cells to metastasize and escape treatment, offering a way to maximize the therapeutic efficacy of each treatment cycle.
- Bryan Q. Spring
- , R. Bryan Sears
- & Tayyaba Hasan
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Perspective |
Designing DNA nanodevices for compatibility with the immune system of higher organisms
This Perspective reviews the molecular, cellular and organismal response pathways that nucleic acid nanodevices are likely to interact with when deployed in living systems, and outlines ways to design nanodevices that either evade or react to the host response.
- Sunaina Surana
- , Avinash R. Shenoy
- & Yamuna Krishnan
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Article |
Symmetry and scale orient Min protein patterns in shaped bacterial sculptures
Using nanofabricated chambers, living bacterial cells can be 'sculpted' into defined shapes, such as squares and rectangles, which can be used to explore the spatial adaptation of Min protein oscillations, a Turing reaction–diffusion pattern that assists cell division.
- Fabai Wu
- , Bas G. C. van Schie
- & Cees Dekker
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Article |
Strong underwater adhesives made by self-assembling multi-protein nanofibres
Strong underwater adhesive fibres are self-assembled by fusing mussel foot proteins with an amyloid-based protein.
- Chao Zhong
- , Thomas Gurry
- & Timothy K. Lu
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Article |
Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines
Nanoparticles with high near-infrared absorption that transit the gut without being absorbed can be used for gastrointestinal imaging using photoacoustic and positron emission tomography.
- Yumiao Zhang
- , Mansik Jeon
- & Jonathan F. Lovell
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Article |
Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery
Single-walled carbon nanotubes are taken up by monocytes in the blood, demonstrating alternative and enhanced tumour delivery.
- Bryan Ronain Smith
- , Eliver Eid Bou Ghosn
- & Sanjiv Sam Gambhir
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Article |
Multifunctional wearable devices for diagnosis and therapy of movement disorders
Integration of diverse nanostructures allows the fabrication of a wearable system capable of storing data, performing diagnostics and delivering drugs.
- Donghee Son
- , Jongha Lee
- & Dae-Hyeong Kim
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Article |
DNA assembly of nanoparticle superstructures for controlled biological delivery and elimination
The DNA assembly of nanomaterials creates designer superstructures for increased efficiency in drug delivery and subsequent breakdown for ease of elimination to mitigate toxicity.
- Leo Y. T. Chou
- , Kyryl Zagorovsky
- & Warren C. W. Chan
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Article |
In vivo biosensing via tissue-localizable near-infrared-fluorescent single-walled carbon nanotubes
Functionalized single-walled carbon nanotubes can be used as highly sensitive and stable nanosensors for the in vivo detection of nitric oxide.
- Nicole M. Iverson
- , Paul W. Barone
- & Michael S. Strano