Bacterial genomics

Bacterial genomics is a scientific discipline that concerns the genome, encompassing the entire hereditary information, of bacteria. Bacterial genomics can, for example, be used to study bacterial evolution or outbreaks of bacterial infections.


Latest Research and Reviews

News and Comment

  • News and Views |

    The secondary metabolite cepacin A is the essential compound made by Burkholderia ambifaria needed for biocontrol of plant pathogens. In this organism, genes responsible for virulence and for cepacin A biosynthesis reside on different replicons, allowing for the engineering of avirulent mutants that retain their biocontrol properties.

    • Tom Coenye
    Nature Microbiology 4, 908-909
  • News and Views |

    Applying the principles of ‘omics’ to urinary tract infection opens up exciting diagnostic and management avenues. Urinary cell-free DNA can be used to gain new insight not only into the spectrum of pathogens present in host urine but also their likelihood to cause disease.

    • Rhana Hassan Zakri
    •  & Jonathon Olsburgh
  • News and Views |

    Genome-wide association studies and genetic analyses have identified a clinically prevalent alteration in the Mycobacterium tuberculosis genome that rewires bacterial propionate metabolism, conditionally reduces antibiotic killing without affecting minimum inhibitory concentrations, and may drive emergence of drug resistance.

    • Thomas Dick
    •  & Véronique Dartois
    Nature Microbiology 3, 971-972
  • News |

    This month's Genome Watch highlights how a better understanding of genotype–phenotype correlation may lead to the design of new diagnostic tests for antimicrobial resistance in clinical settings.

    • Stephanie W. Lo
    • , Narender Kumar
    •  & Nicole E. Wheeler