Adjuvants articles within Nature Materials

Featured

• News & Views | 02 March 2023

  Immunostimulatory nanoparticles go viral

  A polymeric nanoparticle adjuvant containing a Toll-like receptor 7 agonist elicits broad protection against viral challenges.

  • Jorge Huete-Carrasco
  •  & Ed C. Lavelle

• Article
  30 January 2023 | Open Access

  A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2

  A nanoparticle-based adjuvant incorporating a Toll-like receptor 7 agonist elicits cross-reactive antibodies for both dominant and subdominant epitopes and enhances immune responses against multiple variants of influenza and SARS-CoV-2.

  • Qian Yin
  • , Wei Luo
  •  & Mark M. Davis

• News & Views | 22 January 2019

  Next-generation malarial vaccines

  A vaccine platform developed from a synthetic polymeric glyco-adjuvant and reversibly conjugated to an antigen was shown to target dendritic cells leading to cellular and humoral immune response against malaria.

  • Yvette van Kooyk

• Article | 14 January 2019

  Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity

  A vaccine platform has been developed from a polymeric glyco-adjuvant conjugated to an antigen, and is now shown to target dendritic cells via mannose-binding receptors and generate potent cellular and humoral immune response against malaria.

  • D. Scott Wilson
  • , Sachiko Hirosue
  •  & Jeffrey A. Hubbell

• News & Views | 23 January 2018

  Softness makes it better

  An effective adjuvant for the induction of humoural and cellular immunity is achieved by a Pickering emulsion formulation that allows pliability and mobility of loaded antigens.

  • Herman F. Staats
  •  & David J. Burkhart