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| Open AccessTracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion
- Sujatha Chilakala
- , Ye Feng
- & Yan Xu
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Article
| Open AccessEffect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo
- Nicole D. Vincelette
- , Husheng Ding
- & Scott H. Kaufmann
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Article
| Open AccessIL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival
- Yiqian Wang
- , Lisa Richter
- & R. Katherine Hyde
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| Open AccessMidostaurin reduces Regulatory T cells markers in Acute Myeloid Leukemia
- Lucas Gutierrez
- , Miran Jang
- & Houda Alachkar
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| Open AccessTransposable Element Expression in Acute Myeloid Leukemia Transcriptome and Prognosis
- Anthony R. Colombo
- , Timothy Triche Jr.
- & Giridharan Ramsingh
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| Open AccessASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation
- Makoto Saika
- , Daichi Inoue
- & Susumu Goyama
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| Open AccessRepression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML
- Eimear O’ Reilly
- , Sukhraj Pal S. Dhami
- & Eva Szegezdi
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| Open AccessAlteration of Serum Free Fatty Acids are Indicators for Progression of Pre-leukaemia Diseases to Leukaemia
- Ayesha Khalid
- , Amna Jabbar Siddiqui
- & Syed Ghulam Musharraf
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| Open AccessEfficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control
- Purvi M. Kakadia
- , Neil Van de Water
- & Stefan K. Bohlander
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| Open AccessCharacterization of Mutations in the Mitochondrial Encoded Electron Transport Chain Complexes in Acute Myeloid Leukemia
- Sharon Wu
- , Mojtaba Akhtari
- & Houda Alachkar
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| Open AccessA novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity
- Maria Yusenko
- , Anke Jakobs
- & Karl-Heinz Klempnauer
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| Open AccessMediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia
- Roman Hornung
- , Vindi Jurinovic
- & Anne-Laure Boulesteix
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| Open AccessThe histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
- Yaser Heshmati
- , Shabnam Kharazi
- & Julian Walfridsson
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| Open AccessTargeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles
- Tamoghna Mandal
- , Michaela Beck
- & Christian Buske
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| Open AccessProbing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout
- Robert J. MacDonald
- , Jonathan H. Shrimp
- & Andrew Yen
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| Open AccessAutonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells
- Ken Morita
- , Mina Noura
- & Yasuhiko Kamikubo
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Article
| Open AccessTargeting c-KIT (CD117) by dasatinib and radotinib promotes acute myeloid leukemia cell death
- Sook-Kyoung Heo
- , Eui-Kyu Noh
- & Hawk Kim
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| Open AccessThe Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation
- Alissa Marhäll
- , Julhash U. Kazi
- & Lars Rönnstrand
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| Open AccessA novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression
- Abhishek Mangaonkar
- , Ashis Kumar Mondal
- & Ravindra Kolhe
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| Open AccessThe autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells
- Anna M. Schläfli
- , Pauline Isakson
- & Mario P. Tschan
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| Open AccessA Phase II Study of Arginine Deiminase (ADI-PEG20) in Relapsed/Refractory or Poor-Risk Acute Myeloid Leukemia Patients
- Hui-Jen Tsai
- , Shih Sheng Jiang
- & Tsai-Yun Chen
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| Open AccessPrognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature
- Giacomo Volpe
- , David S. Walton
- & Jon Frampton
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| Open AccessEfficacy and safety of different doses of cytarabine in consolidation therapy for adult acute myeloid leukemia patients: a network meta-analysis
- Di Wu
- , Chongyang Duan
- & Size Chen
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| Open AccessTargeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)
- Yanyan Zhang
- , Erika Saavedra
- & Fawzia Louache
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| Open AccessImipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
- Jonathan Metts
- , Heath L. Bradley
- & Kevin D. Bunting
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| Open AccessRole of new Immunophenotypic Markers on Prognostic and Overall Survival of Acute Myeloid Leukemia: a Systematic Review and Meta-Analysis
- A. F. O. Costa
- , D. L. Menezes
- & D. M. Schimieguel
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| Open AccessPP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation
- Chao Hu
- , Mengxia Yu
- & Hongyan Tong
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| Open AccessALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia
- Yungui Wang
- , Jennifer R. Skibbe
- & Xi Jiang
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| Open AccessMechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells
- Jun Ma
- , Xinyu Li
- & Yubin Ge
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Article
| Open AccessDe novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes
- Matheus Rodrigues Lopes
- , João Kleber Novais Pereira
- & Patricia Favaro
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| Open AccessUsing genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML
- Morito Kurata
- , Susan K. Rathe
- & David A. Largaespada
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| Open AccessAML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells
- Marco Saia
- , Alberto Termanini
- & Myriam Alcalay
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| Open AccessHigh expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia
- Lin Fu
- , Huaping Fu
- & Jinlong Shi
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| Open AccessExpression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
- Alexandre Rouette
- , Assya Trofimov
- & Claude Perreault
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| Open AccessSIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation
- Shuang-Nian Xu
- , Tian-Shi Wang
- & Yi-Ping Wang
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| Open AccessFibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions
- Keiki Sugimoto
- , Yasuhiko Miyata
- & Tomoki Naoe
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| Open AccessTetraspanin CD82 Regulates the Spatiotemporal Dynamics of PKCα in Acute Myeloid Leukemia
- Christina M. Termini
- , Keith A. Lidke
- & Jennifer M. Gillette
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| Open AccessFabrication of water-soluble polymer-encapsulated As4S4 to increase oral bioavailability and chemotherapeutic efficacy in AML mice
- Qiang Ma
- , Chuan Wang
- & Haiyan Xu
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| Open AccessThe new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor
- Nadine Sandhöfer
- , Julia Bauer
- & Karsten Spiekermann
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| Open AccessSIRT2 is an unfavorable prognostic biomarker in patients with acute myeloid leukemia
- Ailing Deng
- , Qiaoyang Ning
- & Yaojie Liang
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| Open AccessTargeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia
- Kevin H. Lin
- , Peter S. Winter
- & Kris C. Wood
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Article
| Open AccessSmall molecule activation of NOTCH signaling inhibits acute myeloid leukemia
- Qi Ye
- , Jue Jiang
- & Hudan Liu
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| Open AccessRole of Signal Regulatory Protein α in Arsenic Trioxide-induced Promyelocytic Leukemia Cell Apoptosis
- Chaoyun Pan
- , Dihan Zhu
- & Ke Zen
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| Open AccessmiR-133 regulates Evi1 expression in AML cells as a potential therapeutic target
- Haruna Yamamoto
- , Jun Lu
- & Ai Kotani
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| Open AccessIL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia
- Alexander Kuett
- , Christina Rieger
- & Michael Fiegl
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| Open AccessThe pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia
- Matteo Allegretti
- , Maria Rosaria Ricciardi
- & Agostino Tafuri
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| Open AccessSystematic analysis of hematopoietic gene expression profiles for prognostic prediction in acute myeloid leukemia
- Frederick S. Varn
- , Erik H. Andrews
- & Chao Cheng
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| Open AccessSKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML
- Shuang Ma
- , Ling-Ling Yang
- & Sheng-Yong Yang
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| Open AccessTargeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia
- Genevra Pillinger
- , Amina Abdul-Aziz
- & Stuart A. Rushworth