Abstract
Developments in synchrotron radiation mean that the methodological and technological tools are in place to determine the structures of large multi-component macromolecular machines.
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Acknowledgements
We would like to thank R. Esnouf, R. Mably, A. Perrakis for help and S. Harrison, W. Hol, J. Johnson, Y. Jones, T. Richmond, M. Rossmann, T. Steitz and A. Yonath for sharing some of their thoughts.
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Grimes, J., Stuart, D. Large unit cells and cellular mechanics. Nat Struct Mol Biol 5 (Suppl 8), 630–634 (1998). https://doi.org/10.1038/1322
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DOI: https://doi.org/10.1038/1322