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Volume 16 Issue 2, February 2019

This issue is a special Focus Issue on sexual medicine, including articles on sexuality and sexual function in transgender persons and stem cell therapy for penile fibrosis.

Image of prostate cancer patient-derived organoids supplied by Hatem Sabaawy, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.

Volume 16 Issue 2

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Research Highlights

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Year in Review

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Reviews

  • In this Review, the authors describe the current preclinical research into stem cell therapy for the treatment and prevention of penile fibrotic disorders, including Peyronie’s disease, urethral stricture and corpora cavernosa fibrosis, and highlight their specific mechanisms of antifibrotic activity.

    • Uros Milenkovic
    • Maarten Albersen
    • Fabio Castiglione
    Review Article

  • The penis is a diverse and rapidly evolving structure, much more complex than its fundamental function — sperm transfer — would seem to require. In this Review, experts in the field discuss the drivers of penis evolution, and consider how the penis might be an ideal characteristic on which to focus in studies to link phenotype with genotype.

    • David J. Hosken
    • C. Ruth Archer
    • Nina Wedell
    Review Article

  • Sexual arousal in women comprises two components: genital arousal and subjective arousal. For some women, genital arousal enhances subjective arousal; for others, the two types of arousal are desynchronous. In this Review, Meston and Stanton describe the mechanisms and the relationship between genital and subjective arousal and consider how they assist in diagnosis and treatment of sexual arousal dysfunction and development of treatments for female sexual arousal dysfunction.

    • Cindy M. Meston
    • Amelia M. Stanton
    Review Article

  • Transgender persons can be affected by sexual dysfunctions before, during, after, because of, and despite therapy. In this Review, experts in the field discuss trans sexuality across the gender dysphoric spectrum, and suggest ways in which trans persons can be supported in their sexuality and sexual function.

    • Mats Holmberg
    • Stefan Arver
    • Cecilia Dhejne

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