Several advances in kidney cancer have occurred over the past decade, including the discovery of mutations in chromatin remodelling genes and genomic heterogeneity in clear cell renal cell carcinoma (ccRCC). Altered metabolic patterns in ccRCC and papillary RCC have become apparent, and new drugs for ccRCC have been approved.
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Linehan, W., Ricketts, C. Discoveries, therapies and opportunities. Nat Rev Urol 11, 614–616 (2014). https://doi.org/10.1038/nrurol.2014.262
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DOI: https://doi.org/10.1038/nrurol.2014.262