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In patients with progressive multiple sclerosis, the presence of active inflammation is associated with improved efficacy of anti-inflammatory therapies. However, the frequency of active inflammation in this patient population is unknown, and is the subject of a new study.
An international consortium analysis has shown that stroke location strongly predicts post-stroke cognitive impairment, but the effect could be confounded by the characteristics of the infarct and of different patients. Taking pre-stroke cognition and risk factors into consideration might put information about infarct location into a more appropriate context.
Results of a new study have identified an association between risk of incident Parkinson disease and exposure to NO2, which is released into the atmosphere as a result of burning fuels. Parkinson disease has a long prodromal phase, so these findings suggest an opportunity to apply early prevention strategies.
People with epilepsy have an elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer disease. Here, the authors review evidence that amyloid-β forms part of a shared pathway between epilepsy and cognitive decline.
MRI is an important tool in neuro-oncology but is still predominantly used in a qualitative manner. In this Review, Marion Smits discusses the development of MRI biomarkers for use in neuro-oncology and highlights the clinical potential of quantitative image analysis techniques.
In this Consensus Statement, which is endorsed by the European Headache Federation and the European Academy of Neurology, an expert panel provides recommendations for the diagnosis and management of migraine to support clinical decision-making by general practitioners, neurologists and headache specialists.
In this Perspective, Makhani and Tremlett provide an overview of the evidence for a prodromal phase in multiple sclerosis, discuss possible characteristics and markers of this prodrome, and consider its profound clinical and research implications.
