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Maternal herpes simplex virus encephalitis is a life-threatening condition for the mother and fetus. To treat the maternal disease and prevent infection in the neonate, a multidisciplinary approach is needed. In this Case Study, Sellner and colleagues demonstrate how with early diagnosis, prompt initiation of antiviral treatment, and suitable neurocritical care, a favorable outcome can be achieved in both mother and child.
Pain management is particularly problematic in infants. Fitzgerald and Walker detail the many challenges presented by a developing pain system for the detection and treatment of pain. They then describe the ways in which knowledge of the neurophysiological and neuropharmacological processes that underlie infant pain can improve future management of this vulnerable patient group.
Mirror neurons are motor neurons that discharge both when an individual performs a given motor act and when they observe another individual performing the same act. As Rizzolatti et al. discuss in this Review, the study of the mirror system is providing important insights into the mechanisms that underlie the symptoms of autism, and is also facilitating the development of new neurorehabilitation strategies.