News & Comment

The centrosome is crucial for the microtubule dynamics that underlie the radial migration of developing rodent neurons but is not required for axon growth.

A new study examines thalamic innervation of cortical layer 2/3 pyramidal neurons and models how this thalamic connectivity affects visual responses in these cells.

The ability to be woken from deep sleep by a sound (such as an alarm) is shown to be mediated by a specialized glutamatergic brainstem–mediodorsal thalamic pathway.

Different defensive responses are characterized by transient behavioural and cardiac components, which are constrained by cardiovascular dynamics occurring across the duration of threat exposure.

In a mouse model of tauopathy, neurodegeneration is dependent on the gut microbiota and is affected by apolipoprotein E isoform expression.

In both human radiation-induced brain injury and a mouse model of this condition, activated microglia release chemokines that attract cytotoxic T cells from the periphery to the lesion site, and this exacerbates neuronal damage in the area.

The representational geometry of neural population activity in the somatosensory cortex of mice allows for high flexibility needed to perform complex tasks and for generalization to novel tasks at the same time.

A study in mice reveals the neural pathway through which light regulates glucose metabolism.

Ketamine-induced dissociated states in mice result from the suppression and activation of cortical pyramidal neuron populations that are active and silent during wakefulness, respectively.