News & Comment

  • Research Highlight |

    Certain cellular functions in artificially reperfused pig brains can be restored and maintained several hours after initial loss of cerebral blood flow.

    • Natasha Bray
  • Research Highlight |

    In monkeys, some neurons in the amygdala may simulate a social partner’s decision-making process in a reward-based decision-making task.

    • Darran Yates
  • Research Highlight |

    Certain lasting antidepressant effects of ketamine in a mouse model of depression depend on the restoration of dendritic spines in the prefrontal cortex.

    • Natasha Bray
  • Research Highlight |

    Grid cells in the rat medial entorhinal cortex distort their firing patterns local to a reward in the environment.

    • Natasha Bray
  • Research Highlight |

    Sensory stimulus-induced gamma oscillations reduce pathology and cognitive dysfunction in mouse models of Alzheimer disease.

    • Darran Yates
  • Research Highlight |

    An intracellular molecule acts in a context-dependent manner to suppress responses to irrelevant guidance cues during axon development.

    • Katherine Whalley
  • Research Highlight |

    Neurons expressing corticotropin-releasing factor in the paraventricular nucleus of the hypothalamus of mice show increases and decreases in activity in response to aversive and appetitive stimuli.

    • Natasha Bray
  • Research Highlight |

    In ‘singing’ mice, the motor cortex controls the timing of rapid vocal exchanges to enable turn-taking during social interaction.

    • Katherine Whalley
  • Research Highlight |

    Targeted ultrasound stimulation can specifically modulate the functional connectivity profiles of targeted structures — including deep structures — in the macaque brain, with effects lasting for up to 2 hours following stimulation.

    • Natasha Bray
  • Correspondence |

    • Roberto Cabeza
    • , Marilyn Albert
    • , Sylvie Belleville
    • , Fergus I. M Craik
    • , Audrey Duarte
    • , Cheryl L. Grady
    • , Ulman Lindenberger
    • , Lars Nyberg
    • , Denise C. Park
    • , Patricia A. Reuter-Lorenz
    • , Michael D. Rugg
    • , Jason Steffener
    •  & M. Natasha Rajah
  • Correspondence |

    • Yaakov Stern
    • , Gaël Chételat
    • , Christian Habeck
    • , Eider M. Arenaza-Urquijo
    • , Prashanthi Vemuri
    • , Ainara Estanga
    • , David Bartrés-Faz
    • , Marc Cantillon
    • , Sean A.P. Clouston
    • , Jeremy A. Elman
    • , Brian T. Gold
    • , Richard Jones
    • , Gerd Kempermann
    • , Yen Ying Lim
    • , Anita van Loenhoud
    • , Pablo Martínez-Lage
    • , Silvia Morbelli
    • , Ozioma Okonkwo
    • , Rik Ossenkoppele
    • , Corinne Pettigrew
    • , Allyson C. Rosen
    • , Nikolaos Scarmeas
    • , Anja Soldan
    • , Chinedu Udeh-Momoh
    • , Michael Valenzuela
    •  & Eero Vuoksimaa
  • Research Highlight |

    The sexually dimorphic responses of male and female mice to their young are regulated by the activity of a specific population of neurons in the medial amygdala.

    • Katherine Whalley
  • Research Highlight |

    The neural ensembles within the prelimbic cortex representing remote (long-term) memories undergo time-dependent reorganization.

    • Sian Lewis
  • Research Highlight |

    During nervous system development, secretion of netrin 1 from both the floorplate and the ventricular zone is shown to be important for guidance of commissural axons towards the ventral midline of the spinal cord.

    • Sian Lewis
  • Research Highlight |

    The secreted fragment of the amyloid precursor protein binds to a subunit of GABAB receptors to modulate neurotransmission.

    • Darran Yates
  • Research Highlight |

    In a mouse model of multiple sclerosis, calcium enters neurons via ‘nanoruptures’ in the cell membrane and accumulates in the cytoplasm of axons, driving axonal degeneration.

    • Natasha Bray
  • Research Highlight |

    Sophisticated optical techniques reveal subpopulations of orbitofrontal cortex neurons that mediate interactions between social feedback and feeding.

    • Katherine Whalley
  • Research Highlight |

    Neurons in the mouse postrhinal cortex receive visual inputs from the superior colliculus and respond to visual motion independently of the primary visual cortex.

    • Natasha Bray
  • Research Highlight |

    A mouse model reveals a central role for microglial activation and altered glial cell dynamics in the lasting neurological and cognitive dysfunction following methotrexate chemotherapy.

    • Katherine Whalley
  • Research Highlight |

    Repetitive sensory input induces long-term potentiation of pyramidal cell synapses in mouse somatosensory cortex by activation of higher-order thalamic projections and disinhibition of local interneurons.

    • Sian Lewis
  • Research Highlight |

    In mice, long-term potentiation of hippocampal–nucleus accumbens synapses is required for the formation of reward-related memories.

    • Natasha Bray
  • Research Highlight |

    Meal-associated thermogenesis in brown fat is triggered by the gut hormone secretin and signals to the brain to promote satiation in mice.

    • Katherine Whalley