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This study reports the experimental evolution of the opportunistic fungal pathogen Candida albicans into a non-pathogenic commensal that provides resistance against other pathogens.
This month’s Genome Watch highlights how next-generation sequencing technologies provide crucial information during disease outbreaks and thus inform the public health response.
In this Progress article, McGinn and Marraffini review recent studies that have advanced our understanding of the molecular mechanisms of spacer integration, protospacer capture and primed spacer acquisition, and discuss the future of the field.
Bacterial membrane vesicles can transfer material between cells and function as decoys for antibiotics and phages. This Review provides an overview of different vesicle types, including classic outer-membrane vesicles and newly identified types that are induced by phage-derived autolysins.
Light controls important physiological and morphological responses in fungi. In this Review, Yu and Fischer review the structural basis for light sensing in filamentous fungi and explore the light signalling mechanisms for blue-light photoreceptors, green-light photoreceptors and red-light photoreceptors.
Cyanobacteria have evolved a number of photoreceptor-controlled mechanisms that enable them to sense and respond to environmental light conditions. In this Review, Kehoe and Wiltbank examine physiological responses that are controlled by members of the phytochrome photoreceptor superfamily and discuss the signal transduction pathways through which these photoreceptors operate.
This Consensus Statement presents the barriers that currently prevent the timely development and implementation of novel and rapid antimicrobial susceptibility testing platforms, including the costs involved, uptake of new tools, legal and regulatory aspects, difficulties conducting clinical trials and quality control, and presents possible solutions.
