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Protozoan parasites produce extracellular vesicles to communicate with the host and within the parasite population. In this Progress article, Hajduk and colleagues review the production and effects of extracellular vesicles from parasites, includingPlasmodium spp., Trichomonas vaginalisand kinetoplastids.
In this Progress article, Stephanie Karst describes how the gut microbiota promotes intestinal infection by enteric viruses. She discusses direct mechanisms by which bacteria stabilize viral particles and facilitate viral attachment to host cells, and indirect mechanisms by which the microbiota suppresses antiviral immune responses.
Although the mechanisms of CRISPR–Cas interference have largely been elucidated, how new sequence memories are stored had remained unknown. In this Progress article, Amitai and Sorek discuss recent advances in the study of this adaptation stage of CRISPR immunity.