In Brief in 2019

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  • This study shows that a plant pathogen uses extracellular DNases as a defence mechanism against host-secreted extracellular DNA.

    • Andrea du Toit
    In Brief
  • This study shows that naked and quasi-enveloped hepatitis A virus virions enter cells via similar endocytic pathways, but uncoating of capsids is temporally and spatially different.

    • Andrea du Toit
    In Brief
  • This study shows that staphylococcal leukocidins target endothelial cells to cause host lethality.

    • Andrea du Toit
    In Brief
  • The findings of this study suggest that Zika virus differentially reprogrammes glucose metabolism in humans and mosquitoes, which affects host cell death and survival.

    • Andrea du Toit
    In Brief
  • This study reports that the incorporation of antimalarial drugs into insecticide-treated bed nets could be a promising transmission-blocking strategy.

    • Andrea du Toit
    In Brief
  • This study reports that the phosphorylation of a paramyxovirus protein switches the infection phenotype from lytic to persistent.

    • Ashley York
    In Brief
  • A recent study finds that pre-existing immunity to dengue virus is associated with a reduction in Zika virus transmission.

    • Ashley York
    In Brief
  • This study found that a lipase secreted by the opportunistic pathogen Staphylococcus aureus promotes immune evasion.

    • Ashley York
    In Brief
  • This study shows that the interaction between two sessile soil bacteria leads to emergence of interspecies social spreading.

    • Andrea Du Toit
    In Brief
  • This study reports a large population cohort study in which the authors correlate microbial taxa with quality of life and the incidence of depression.

    • Andrea Du Toit
    In Brief
  • The description of a method to measure the HIV-1 reservoir that quantifies intact and defective proviruses.

    • Andrea Du Toit
    In Brief
  • This report shows that a non-structural protein of a persistent plant virus can induce the apoptotic response to promote viral transmission.

    • Andrea Du Toit
    In Brief
  • This study used a large-scale metagenomic-assembly approach and uncovered thousands of new species associated with the human microbiome.

    • Andrea Du Toit
    In Brief