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Michael Levin and colleagues discuss how computer-designed organisms ― biobots and xenobots ― are driving a new research field with applications in biomedicine and engineering, and associated ethical and philosophical questions.
Circadian clocks control our immune system, infections and pharmacokinetics. Ray and Reddy argue that better understanding the effects of circadian biology on SARS-CoV-2 infection would improve COVID-19 management.
Shivashankar and Uhler propose a link between cell mechano-genomics and coronavirus replication with implications for understanding the pathogenicity of SARS-CoV-2.