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Graham Anderson describes a 2001 study by Rodewald and colleagues that provided the first experimental evidence for thymic epithelial cell progenitors.
Haemocytes inDrosophila melanogasterfacilitate antiviral immunity by amplifying and systemically disseminating RNA interference-mediated responses via exosome-like vesicles. Moreover, they allow for immune memory, akin to adaptive immune responses in mammals.
Microbial metabolites can protect mice from diabetes by decreasing the frequency of autoreactive T cells and promoting the frequency of regulatory T cells.
Linda Sherman describes a 1991 study by Hans-Georg Rammensee and colleagues that defines allele-specific motifs required for the binding of peptides to MHC molecules.
High-resolution proteomics analysis of human immune cells reveals new social networks and establishes a framework for future study of intercellular communication.
Pregnant mice show weaker immune responses to pandemic strains of influenza virus than non-pregnant mice, and this leads to the emergence of more virulent strains of influenza.