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Cancer-associated cachexia is a disorder characterized by the loss of skeletal muscle and adipose tissue that is driven by reduced food intake and metabolic changes. In this Primer, Baracos et al. discuss emerging mechanistic insights and the approach to caring for vulnerable patients with cancer-associated cachexia.
Antiphospholipid syndrome is an autoimmune disease associated with a variety of symptoms, including thrombosis and obstetrical complications. This Primer provides an update on the epidemiology, pathogenesis, diagnosis and therapeutic aspects and offers an outlook on future research topics.
The prevalence of food allergy has increased over recent decades and is now recognized as a substantial public health burden, particularly in developed countries. This Primer provides a comprehensive overview of advances in the field of food allergies, covering mechanistic understanding, diagnostics, prevention and management.