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Cancer-associated cachexia leads to progressive functional impairment, cancer-related mortality and treatment-related complications. This PrimeView highlights some of the emerging research to tackle this important syndrome.
Cancer-associated cachexia is a disorder characterized by the loss of skeletal muscle and adipose tissue that is driven by reduced food intake and metabolic changes. In this Primer, Baracos et al. discuss emerging mechanistic insights and the approach to caring for vulnerable patients with cancer-associated cachexia.
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and anti-β2-glycoprotein 1 antibodies. This PrimeView focuses on the pathophysiology of APS, which is mainly characterized by thrombosis and obstetrical complications.
Antiphospholipid syndrome is an autoimmune disease associated with a variety of symptoms, including thrombosis and obstetrical complications. This Primer provides an update on the epidemiology, pathogenesis, diagnosis and therapeutic aspects and offers an outlook on future research topics.
This PrimeView highlights the main hypotheses that explain the risks of developing food allergy, which have implications for potential preventive strategies.
The prevalence of food allergy has increased over recent decades and is now recognized as a substantial public health burden, particularly in developed countries. This Primer provides a comprehensive overview of advances in the field of food allergies, covering mechanistic understanding, diagnostics, prevention and management.
