A schematic of trachoma


Trachoma is one of 20 diseases and disease groups designated as neglected tropical diseases by the WHO. It is the most common infectious cause of blindness. 


  • Cover image NRDP

    Primers soon to be featured in the journal include Acute graft-versus-host disease, Primary central nervous system lymphoma, Oppositional defiant disorder, and Imprinting disorders.

  • A new Comment article discusses the environmental effects of health care

    Planetary and human health are inseparably connected; yet, health-care systems produce considerable amounts of greenhouse gas emissions, waste and pollution. This Comment discusses how health care affects the environment and how we can mitigate these effects.

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    Finding it hard to navigate the flood of scientific literature? Take a look at this animation to learn how Nature Reviews can help you stay up-to-date in your field by filtering and highlighting the most impactful research, or visit www.springernature.com/naturereviews


  • Worldwide, the prevalence of obesity in children and adolescents remains high or is increasing. This Primer by Lister and colleagues discusses the epidemiology, mechanisms, diagnosis, prevention and management of obesity in this age group. The authors also highlight patient quality of life and areas for further research.

    • Natalie B. Lister
    • Louise A. Baur
    • Martin Wabitsch
  • Young-onset colorectal cancer occurs in individuals younger than 50 years and is increasing in incidence worldwide. This Primer provides an overview of the epidemiology, diagnosis, screening, prevention, pathophysiology and management of this cancer and its impact on patient quality of life.

    • Manon C. W. Spaander
    • Ann G. Zauber
    • Ernst J. Kuipers
  • Helicobacter pylori infection causes chronic gastritis and can lead to severe gastroduodenal pathologies, including peptic ulcer and gastric cancer. This Primer summarizes the epidemiology, pathophysiology, diagnosis and management of this infection, and discusses patient quality of life and open research questions.

    • Peter Malfertheiner
    • M. Constanza Camargo
    • Sebastian Suerbaum
  • Chikungunya fever is an acute febrile illness caused by chikungunya virus, a mosquito-borne alphavirus. This Primer by Bartholomeeusen and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of chikungunya fever, and discusses patient quality of life and open research questions for this condition.

    • Koen Bartholomeeusen
    • Matthieu Daniel
    • Kevin K. Ariën
  • This Primer by Cordonnier and colleagues describes the epidemiology, aetiology, pathophysiology, diagnosis and treatment of intracerebral haemorrhage.

    • Laurent Puy
    • Adrian R. Parry-Jones
    • Charlotte Cordonnier
  • Monogenic diabetes encompasses forms of diabetes that result from a single pathogenic genetic alteration and usually have an early onset. This Primer gives an overview of the epidemiology, pathophysiology, diagnosis and treatment of these conditions, as well as patient quality of life and open research questions.

    • Amélie Bonnefond
    • Ranjit Unnikrishnan
    • Philippe Froguel
  • The concept of syndemics specifies which, where and how disease concentrations and interactions emerge and persist. Recognizing multimorbidity within a population or region is fundamental to syndemics because multimorbid conditions often share upstream drivers, including social inequalities. Applying syndemics to health care can inform clinical and policy interventions.

    • Justin Dixon
    • Emily Mendenhall
  • Refugees are a growing and dynamic global population that require theories, programmes and policies to improve community-based integration and health care. Although many gender, cultural and system barriers persist, countries must innovate to support migration flow, universal care coverage, trauma-informed approaches and health equity for refugees.

    • Kevin Pottie
    • Doug Gruner
  • Current medical education propagates bias and power imbalances in medical institutions, which cascade into professional practices and organizations. To serve the needs of all, we need an understanding of how modern medicine was set up, the biases that are embedded in the structures of health care and strategies to transform those structures.

    • Amali U. Lokugamage
    • Rupa Marya
  • Sexual and gender minorities (SGM) experience negative attitudes, stigma, denial of care or low-quality care from health-care providers. Increased awareness and adequate training of health-care professionals and students are required to reduce biases and barriers to care for SGM people.

    • Monica Malta
  • Specific chromosomal abnormalities are associated with development of multiple myeloma and its precursor syndromes. This poster explores the process of plasma cell development, and the types and frequencies of chromosomal abnormalities and other genetic alterations that are involved in development and progression of multiple myeloma.

    • Aneta Mikulasova
    • Gareth J. Morgan
    • Brian A. Walker
A group of women with diverse backgrounds and physiques are standing together, supporting each other and looking ahead.

Women’s health

Research into women’s health has suffered from historical neglect and lack of funding.


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