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Seven pharmaceutical companies and the Innovative Medicines Initiative have launched a €196 million project in a bid to boost academic and industry lead discovery.
Last year saw the largest loss of revenue yet from major drugs due to patent expiries, but a continuation of 2011's higher level of drug approvals and new initiatives to address R&D challenges provide hope for the future.
After more than a decade of clinical development for cancer and numerous failures, Phase III trials of cyclin-dependent kinase inhibitors are beginning.
Long-standing efforts to develop drugs that target MEKs could soon come to fruition, moving the frontier to how best to combine them with other cancer therapies.
Less than a decade on from genetic studies indicating the potential of PCSK9 as a target to affect cholesterol metabolism, two PCSK9 inhibitors are moving into late-stage development.
Economists hope they can attract billions of dollars for drug R&D by securitizing research projects. Could they close the innovation gap in the process?
After decades of stubbornly slow progress in asthma drug development, recent results from a trial of GlaxoSmithKline's mepolizumab hint at a brighter future.
Three prevention trials in asymptomatic Alzheimer's disease patients will attempt to validate the amyloid hypothesis, evaluate biomarkers and set the stage for drug approvals.
A new €32 million project aimed at understanding drug-induced liver injury is the latest of several collaborative efforts that could help drug firms better test for candidate-killing toxicity signals.
Toll-like receptor agonists have hit another setback with the Phase II failure of Idera's IMO-2055, but these immunotherapies may still make a comeback if appropriate combinations with vaccine antigens or anticancer drugs can be identified.
With the first biosimilar version of a monoclonal antibody now under regulatory review in the European Union, which R&D strategies are innovators relying on to counteract competition?
Researchers are starting to use high-throughput genomic technologies to guide patients into trials of experimental cancer therapies, but is our understanding of the cancer genome ready yet?