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As funding for translational research becomes increasingly available, attention is turning to how to build networks and career structures that will help investigators in the field to flourish.
Following the high-profile ENHANCE trial, in which addition of the cardiovascular drug ezetimibe to statin therapy did not result in additional improvement in an imaging-based measure of atherosclerosis, what are the implications for such studies in the future?
As Novo Nordisk joins Pfizer in abandoning an inhaled insulin product, what are the implications for the future of targeting the lung for delivering protein therapeutics?
A more widespread adoption of an approach taken by a new scheme in which payment for an anticancer drug is linked to treatment response might create stronger incentives and opportunities for the discovery and application of clinically relevant biomarkers.
Dramatic increases in the prevalence of multidrug-resistant bacteria have put the spotlight on the lack of new antibacterials coming through the pipeline. How might regulatory guidance for clinical trials of antibacterials help tackle this shortfall?