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A spectrum of common illnesses that constitute risk factors for cardiovascular diseases is associated with both cognitive impairment and high population mortality. Many clinical trials are focused on the prevention of cardiovascular mortality, but cognitive impairment should now be regarded as a similarly important outcome.
To achieve timely restoration of coronary flow in patients with acute myocardial infarction, the decision to call in the cardiac catheterization team has moved ever earlier, and is often made before cardiologist evaluation. Door-to-balloon times have been reduced, but the price of this success is an increase in 'false alarms'.
Arterial injury is an inevitable consequence of all interventional coronary procedures. In this Review, the authors explain the importance of a competent, functional endothelium for vascular health and describe the processes that are required for full endothelial recovery after arterial injury.
Transcatheter aortic valve implantation is increasingly being used to treat aortic valve disease in patients at high surgical risk, but data indicate an emerging association between the procedure and incident conduction abnormalities. The authors review the frequency, potential anatomical and procedural causes, and clinical consequences of these adverse effects.
Cardiovascular disease (CVD) is an under-recognized major health problem among women in South-East Asia, which is compounded by psychological, social, and cultural issues as well as by misconceptions about the disease. In this Review, leading female cardiologists from South-East Asia discuss the changing prevalence of CVD and cardiovascular risk factors among women in the region. The 'heart health awareness' strategies implemented by governments and national heart associations are reviewed, together with the barriers and challenges to improving women's cardiovascular health in South-East Asia.
The role of biomarkers in the management of patients with acute heart failure (HF) has evolved rapidly in the past several years to meet the need for earlier diagnosis, better risk stratification, and cost-effective treatment. In this state-of-the-art Review, Drs Maisel and Choudhary provide an update on biomarkers used for the diagnosis and management of patients with acute HF, as well as non-HF markers indicative of damage to the organs and systems most-commonly affected by HF.
