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Thiopurines are effective anti-inflammatory, anticancer and immunosuppresive drugs. However, azathioprine is also a carcinogen. So, how do thiopurines exert their therapeutic and carcinogenic effects?
High-dimensional genomic and proteomic data are now commonplace in cancer research. This Review aims to help biologists understand the properties of high-dimensional data spaces and how these affect our ability to derive meaningful information from the data.