News & Comment

Filter By:

Article Type
Year

  • This paper maps oestrogen receptor-α (ERα) binding to chromatin in frozen samples of breast tumours to identify changes in ERα-mediated gene expression, which are modulated by FOXA1 and which correlate with prognosis.

    • Gemma K. Alderton
    Research Highlight

  • Whole-genome sequencing indicates few genetic changes in retinoblastoma and hints at epigenetic changes instead.

    • Nicola McCarthy
    Research Highlight

  • Two papers indicate the importance of TAZ in cancer biology.

    • Mhairi Skinner
    Research Highlight

  • Regulation of a splicing factor kinase by the Wilms' tumour suppressor WT1 contributes to alternative splicing ofVEGFA.

    • Sarah Seton-Rogers
    Research Highlight

  • A recent study proposes a new drug combination strategy to target drug-resistant chronic myeloid leukaemia.

    • Darren J. Burgess
    Research Highlight

  • Cancer cells target active SRC for autophagy when SRC signalling is deregulated through the loss of focal adhesion kinase.

    • Nicola McCarthy
    Research Highlight