Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In this study, Linde et al. demonstrate how therapeutic activation of neutrophils leads to tumour eradication and reduced metastatic seeding in multiple mouse models of cancer.
In this Tools of the Trade article, Susan Bullman describes the development and use of INVADEseq, a single-cell RNA sequencing approach that facilitates the simultaneous capture of both eukaryotic and bacterial transcripts in host cells to functionally understand the intratumoural microbiota.
In this Tools of the Trade article, Lee describes Select-seq, a novel method for generating epitranscriptomic data from microniches within the tumour. The author reveals how the method can be used to identify novel biomarkers from rare cell subpopulations such as cancer stem cells in tumours.
In this study, Jung-Garcia et al. use in vitro and in vivo modelling to demonstrate the role of LAP1 in promoting melanoma cell invasion and highlight its link to metastatic dissemination.
This study shows how the selective immune pressure in early-stage tumours drives interferon-γ-dependent metabolic reprogramming in cancer cells to mediate immune escape.
To understand malignant progression, Yuan et al. delineate the complex crosstalk between cancer stem cells and their microenvironment that is initiated by oncogenic RAS.
