Volume 41 Issue 5, April 2016

Volume 41 Issue 5

Microglia recruitment to amyloid-beta (Aβ) plaques in the brain of APPswe/PS1 Alzheimer's disease (AD) mouse model: Triple 6E10 (Aβ)/Iba1 (microglia)/DAPI (nucleus) immunofluorescence staining that shows Aβ-immunoreactive microglia (i.e. microglia internalizing Aβ) surrounding Aβ plaques. Image was acquired by using laser scan confocal microscopy with a 60X objective. Cover image courtesy of ElAli A, Bordeleau M, Thériault P, Lampron A, Filali M, and Rivest S. For more information, see the paper, doi.10.1038/npp.2015.279, on page 1297.

Fluorescent in situ hybridization of the mouse ventral tegmental area lAβeled for tyrosine hydroxylase (red), brain-derived neurotrophic factor (green), or glutamate decarboxylase (blue). Cover image courtesy of Christopher Cook and Juli Wu, who processed the tissue, and Ann Taylor, who captured and analyzed the image.

Correlated groups of genes whose expression in dorsolateral prefrontal cortex is associated with bipolar disorder. Cover image courtesy of Nirmala Akula and Francis J McMahon, Human Genetics Branch, National Institute of Mental Health Intramural Research Program (NIMH-IRP), National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.

In Memoriam

Original Articles