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Volume 7 Issue 1, January 2012

DNA-based assembly can be used to create ordered three-dimensional arrays of inorganic nanoparticles in which the nanoparticles are held in place by short strands of DNA that are attached to their surface. Using two different types of nanoparticles allows a wider variety of binary superlattices to be created. Now Chad Mirkin and co-workers have shown that replacing some of the nanoparticles with hollow spacer particles made only of DNA allows an even wider variety of structures to be created, including one that has never been seen before. This artist's impression shows a hexagonal superlattice formed by replacing some of the gold nanoparticles (red spheres; not to scale) in an AB2 lattice with spacer nanoparticles (grey spheres). The background image is a small-angle X-ray diffraction pattern.

Letter p24

IMAGE: JOSHUA I. CUTLER, KE ZHANG, AND EVELYN AUYEUNG

COVER DESIGN: ALEX WING

Thesis

  • The golem stories of Jewish history can provide a framework for thinking about some of the ethical questions involved in nanotechnology and nanomedicine, as Chris Toumey explains.

    • Chris Toumey
    Thesis

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Research Highlights

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News & Views

  • A four-level conductance switch can be created by using a scanning tunnelling microscope to remove a hydrogen atom from the central cavity of a porphyrin molecule.

    • Peter Liljeroth
    News & Views
  • Bioinspired nanoreactor arrays can be used to controllably mix subattolitre volumes of liquids.

    • Aldo Jesorka
    • Owe Orwar
    News & Views
  • Laser-based imaging can distinguish between semiconducting and metallic nanotubes in vitro and in vivo, offering a way to study the interactions of carbon nanostructures in biological systems without the use of labels.

    • Kevin Tvrdy
    • Michael S. Strano
    News & Views
  • The cycle of cell birth, growth and division can affect the uptake and dilution of nanoparticles in cells, suggesting that the evolution of nanoparticle dose within a cell population is linked to the life cycle of cells.

    • Huw Summers
    News & Views
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Review Article

  • Nanodiamonds have excellent mechanical and optical properties, high surface areas and tunable surface structures. This article reviews the synthesis of nanodiamonds and their use in a variety of applications including drug delivery, tissue engineering and nanocomposites.

    • Vadym N. Mochalin
    • Olga Shenderova
    • Yury Gogotsi
    Review Article
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Corrigendum

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