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  • Focus |

    Specially commissioned Reviews and a Perspective provide a guide to the maturing field of single-molecule analysis and two original research papers describe complementary advances in nanoscale visualization.

  • Special |

    Nature Methods' Method of the Year 2007 goes to next-generation sequencing. This series of articles showcase how these novel sequencing methods came into their own in 2007 and the incredible impact they promise to have in a variety of research applications. The Methods to Watch feature provide a glimpse and a wish list for future Methods of the Year.

  • Milestone |

    Milestones in DNA Technologies is a collaborative project involving three journals - Nature,Nature MethodsandNature Reviews Genetics- and celebrates more than half a century of discoveries and applications of DNA technologies.

  • Focus |

    A series of specially commissioned Commentaries, Reviews and Perspectives discuss the use of mass spectrometry in established approaches to proteomics as well as emerging technologies.

  • Focus |

    Eight especially commissioned Perspective articles that discuss practical questions surrounding the use of RNA interference in mammalian cells, as a tool to knock down a specific gene of interest and as a resource for functional genomics screens.

  • Focus |

    A series of review articles and other content discussing the principles of fluorescence and different imaging modalities along with practical advice.