Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
The CPJUMP1 Resource comprises Cell Painting images and profiles of 75 million cells treated with hundreds of chemical and genetic perturbations. The dataset enables exploration of their relationships and lays the foundation for the development of advanced methods to match perturbations.
An updated version of the Waxholm Space atlas of the rat brain includes more detailed annotations of several brain regions, including the cortex, striatopallidal region, midbrain and thalamus, expanding the previous version with 112 new and 57 revised structures.
EmbryoNet is an automated approach to the phenotyping of developing embryos that surpasses experts in terms of speed, accuracy and sensitivity. A large annotated image dataset of zebrafish, medaka and stickleback development rounds out this resource.
This resource describes a collection of neurons from a variety of light microscopy-based datasets, which can serve as a gold standard for testing automated tracing algorithms, as shown by comparison of the performance of 35 algorithms.
The outbreak.info genomic reports provides comprehensive and detailed information about SARS-CoV-2 lineages and mutations worldwide, which facilitates near real-time genomic surveillance.
Spatial Omics DataBase (SODB) is a web-based platform for sharing and analyzing >25 types of spatial omics data. SODB promotes data reuse, offers novel visualization tools and can streamline development of omics analysis tools.
The AlphaFill algorithm transplants missing small molecules and ions from experimentally determined structures to predicted protein models in the AlphaFold protein structure database. All AlphaFill entries are available for visual inspection and download through the AlphaFill website.
This Resource presents and analyzes four datasets containing both gene expression and morphological profile data for cells subjected to hundreds to thousands of chemical or genetic perturbations and highlights their complementary nature.
This Resource presents a serial block-face EM dataset of the whole larval zebrafish brain, including automated segmentation of neurons, detection of synapses and reconstruction of circuitry for visual motion processing.
This work presents a quantitative draft of the mouse proteome and phosphoproteome constructed from 41 healthy tissues covering 15 major anatomical systems and 66 cell lines.
This three-dimensional structural SARS-CoV-2–human interactome web server allows hypothesis-driven exploration of the mechanisms of SARS-CoV-2 pathology and host response.
The LIVECell dataset comprises annotated phase-contrast images of over 1.6 million cells from different cell lines during growth from sparse seeding to confluence for improved training of deep learning-based models of image segmentation.
A protein expression atlas of transcription factors charted onto cell lineage maps of Caenorhabditiselegans development that uncovers mechanisms of spatiotemporal cell fate patterning and regulators of embryogenesis.
GPCRmd is a community-driven online platform to visualize, analyze and share G-protein-coupled receptor (GPCR) molecular dynamics data. It currently contains simulation data representing 100% of GPCR classes, 71% of receptor subtypes and 80% of GPCR families.
The meltome atlas compiles the thermal stability of 48,000 proteins across 13 species ranging from archaea to humans, providing a resource for analyzing protein stability in the context of function and interactions.