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  • Armed with a rapidly maturing toolbox for single-cell analysis, scientists are threading together multiple layers of omic data to assemble rich portraits of cellular identity and function.

    • Michael Eisenstein
    News Feature
  • Miniaturized, head-mounted fluorescent microscopes give researchers a clear view of neuronal activity as animals freely explore and interact with their surroundings.

    • Michael Eisenstein
    News Feature
  • Recent advances in cryo-electron microscopy are enabling researchers to solve protein structures at near-atomic resolutions, expanding the biological applicability of this technique. Michael Eisenstein reports.

    • Michael Eisenstein
    News Feature
  • Light-sheet fluorescence microscopy techniques are enabling researchers to achieve dynamic, long-term imaging and three-dimensional reconstruction of specimens ranging from single cells to whole embryos.

    • Michael Eisenstein
    News Feature
  • Single-cell genome and transcriptome sequencing methods are generating a fresh wave of biological insights into development, cancer and neuroscience. Kelly Rae Chi reports.

    • Kelly Rae Chi
    News Feature
  • Analysis of a preselected group of proteins delivers more precise, quantitative, sensitive data to more biologists. Vivien Marx reports.

    • Vivien Marx
    News Feature
  • Precise ways to modify the genome arose from unexpected places. Monya Baker reports.

    • Monya Baker
    News Feature
  • Optogenetics grows from an idea into a discipline. Monya Baker reports.

    • Monya Baker
    News Feature
  • Now that the generation of induced pluripotent stem cells is becoming routine, researchers can get on to the more exciting prospect of using the cells to make discoveries in disease and basic biology. Monya Baker reports.

    • Monya Baker
    News Feature
  • After a long period of measured development and a recent surge of technical advances driven by physicists, super-resolution fluorescence microscopy emerged in 2008 as a powerful tool for biologists. Kelly Rae Chi reports.

    • Kelly Rae Chi
    News Feature
  • In 2007, the next-generation sequencing technologies have come into their own with an impressive array of successful applications. Kelly Rae Chi reports.

    • Kelly Rae Chi
    News Feature