Method to Watch

Filters

  • Method to Watch |

    Synthetic approaches help to dissect the complexity of microbial interactions.

    • Lei Tang
  • Method to Watch |

    Tools are needed to study phase behaviors of membraneless compartments in living cells.

    • Lei Tang
  • Method to Watch |

    Engineered genome structure explores function.

    • Nicole Rusk
  • Method to Watch |

    Machine learning approaches that include deep learning are moving beyond image classification to change the way images are made.

    • Rita Strack
  • Method to Watch |

    New technologies bring single-cell proteomics closer to reality.

    • Allison Doerr
  • Method to Watch |

    The rich repertoire of T cell receptors is awaiting large-scale profiling.

    • Nicole Rusk
  • Method to Watch |

    Genetically encoded neurotransmitter sensors will shed light on neuronal communication.

    • Nina Vogt
  • Method to Watch |

    Recent advances in mass spectrometry imaging enable label-free molecular mapping in single cells and in 3D.

    • Allison Doerr
  • Method to Watch |

    New X-ray free-electron (XFEL) facilities will broaden access to this technology, facilitate methods development, and push boundaries in structural biology.

    • Allison Doerr
  • Method to Watch |

    Sophisticated barcoding approaches are transforming cell lineaging.

    • Tal Nawy
  • Method to Watch |

    It will soon be commonplace to localize gene expression in tissues.

    • Tal Nawy
  • Method to Watch |

    Sequencing and imaging bring unique aspects to genome architecture.

    • Nicole Rusk
  • Method to Watch |

    Higher volumetric imaging rates shed light on the dynamics in neuronal networks.

    • Nina Vogt
  • Method to Watch |

    Ex vivo organoid culture could revolutionize biology, but variability must be understood.

    • Natalie de Souza
  • Method to Watch |

    The changing face of super-resolution imaging

    • Rita Strack
  • Method to Watch |

    Cryo-electron tomography may facilitate in situ structural biology on a proteomic scale.

    • Allison Doerr
  • Method to Watch |

    Single-cell sequencing is poised to elucidate how cells contribute to tissue function.

    • Tal Nawy
  • Method to Watch |

    The ability to measure the metabolome on a global scale lags behind other omics techniques.

    • Allison Doerr
  • Method to Watch |

    Having revolutionized DNA editing, CRISPR turns to RNA.

    • Nicole Rusk
  • Method to Watch |

    Methods for imaging multiple targets in a single cell are breaking the color barrier.

    • Rita Strack
  • Method to Watch |

    Methods to systematically map the distribution of proteins in cells are evolving.

    • Natalie de Souza
  • Method to Watch |

    New approaches are needed to see the dynamics of 3D chromatin structure at high resolution and throughput.

    • Nicole Rusk
  • Method to Watch |

    Optogenetic manipulation of neurons at cellular resolution holds promise for the dissection of neural microcircuitry.

    • Nina Vogt
  • Method to Watch |

    New computational tools learn complex motifs from large sequence data sets.

    • Nicole Rusk
  • Method to Watch |

    Integrated molecular profiles of single cells will provide mechanistic insights into gene regulation and heterogeneity.

    • Tal Nawy
  • Method to Watch |

    Better protein-labeling strategies will improve imaging.

    • Rita Strack
  • Method to Watch |

    Advances in time-resolved crystallography make it possible to follow ever more rapid protein structural changes.

    • Allison Doerr
  • Method to Watch |

    Methods to profile and characterize the function of noncoding RNAs will emerge.

    • Nicole Rusk
  • Method to Watch |

    As the CRISPR-Cas system matures, specificity, efficacy and maybe even a eukaryotic nuclease are being considered.

    • Nicole Rusk
  • Method to Watch |

    A closer look into the depths of organs such as the brain is within reach.

    • Nina Vogt
  • Method to Watch |

    Correlated light and electron microscopy (CLEM) is particularly powerful when applied in super-resolution.

    • Natalie de Souza
  • Method to Watch |

    Data-independent acquisition (DIA) mass spectrometry may change how proteomic data are generated.

    • Allison Doerr
  • Method to Watch |

    Genetically encoded voltage indicators are on the brink of allowing neuronal activity to be directly imaged in vivo.

    • Nina Vogt
  • Method to Watch |

    Nanopores hold promise for single-protein characterization.

    • Tal Nawy
  • Method to Watch |

    Protein structures can be determined from microcrystals using X-ray and electron diffraction.

    • Allison Doerr
  • Method to Watch |

    Biologists need methods for sequencing genetic material directly from intact tissues.

    • Tal Nawy