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    We are seeking a locum editor to join our team for a 6-month position. Candidates with genetics, genomics or genome engineering expertise are particularly encouraged to apply; previous editorial experience not required. A great training opportunity!

  • Virus particle

    The COVID-19 pandemic has been marked by speedy scientific progress boosted by decades of methods development for basic biological research. Here, we highlight some of the key advancements that have facilitated the scientific response to SARS-CoV-2.

  • Complete human genome

    The Telomere-to-Telomere (T2T) Consortium has generated the first complete human genome. Some of the methods and results from the consortium are presented here along with expert commentary on this milestone.

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    The 2nd Frontiers in Electron Microscopy for Physical and Life Sciences will take place at Princeton University on September 28-30, 2022. Join researchers across physical and life sciences, plus editors from Nature Methods, Nature, Nature Materials and Nature Communications, to discuss cutting-edge technology developments in this field.

Nature Methods is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.


  • Researchers have discovered two naturally occurring channelrhodopsins for potassium ion transport that can be used in optogenetic applications.

    • Rita Strack
    Research Highlight
  • Stem cell-derived endothelial cell subtypes enable study of viral tropism.

    • Madhura Mukhopadhyay
    Research Highlight
  • In this issue, we are delighted to launch a new regular feature: the Creature Column.

  • Imputing missing parental genotypes sharpens estimates of direct genetic effects.

    • Lin Tang
    Research Highlight

Method of the Year 2021: Protein structure prediction

Protein structure prediction is our Method of the Year 2021, for the remarkable levels of accuracy achieved by deep learning-based methods in predicting the 3D structures of proteins and protein complexes, essentially solving this long-standing challenge.


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