Reviews & Analysis

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  • Cells use differences in the binding rates between the extracellular matrix and integrin adhesion receptors to sense matrix rigidity.

    • José R. García
    • Andrés J. García
    News & Views
  • The nuclei of naive mouse embryonic stem cells that are transitioning towards differentiation expand when the cells are stretched and contract when they are compressed. What drives this auxetic phenotype is, however, unclear.

    • Ning Wang
    News & Views
  • Physical cues from the extracellular environment influence the lineage commitment of stem cells. Now, experiments on human mesenchymal stem cells cultured on photodegradable hydrogels show that the cells' fate can also be determined by past physical environments.

    • Jeroen Eyckmans
    • Christopher S. Chen
    News & Views
  • Soft culture substrates improve the yield of functional motor neurons derived from human pluripotent stem cells.

    • Emily Rhodes Lowry
    • Christopher E. Henderson
    News & Views
  • Enhancing the temperature at which superconductivity is observed is a long-standing objective for materials scientists. Recent tantalizing experiments suggest a possible route for achieving this.

    • N. Peter Armitage
    News & Views
  • By embedding organic dyes in a suitably designed optical microcavity it is possible to strongly mix light and matter excitations, forming states known as microcavity polaritons. These hybrid light–matter states are used to demonstrate energy transfer between organic molecules over long distances.

    • Russell J. Holmes
    News & Views
  • The remarkable properties of a bivalve shell that enable it to protect the animal against its predators could inspire the design of new lightweight armour materials.

    • Robert O. Ritchie
    News & Views
  • A high-throughput approach combining combinatorial deposition of materials with parallel blow-forming speeds up the discovery rate of bulk metallic glasses that can be easily formed into complex shapes.

    • Dan B. Miracle
    News & Views
  • The demonstration of amplified spontaneous emission from thin films of perovskites could pave the way to solution-processed low-cost lasers that can be easily tuned across the entire visible spectrum.

    • Frédéric Laquai
    News & Views
  • Nacre-like bulk ceramics with a unique combination of high toughness, strength and stiffness can be produced from brittle constituents by an ice-templating approach.

    • André R. Studart
    News & Views
  • It is now possible to fabricate high-quality thin films of spin ice materials. At higher temperatures, they exhibit the hallmarks of a regular spin ice, but at lower temperatures their physics deviate significantly from the properties observed in the bulk.

    • Oleg Petrenko
    News & Views
  • High-shear mixing is now shown to be an effective approach for the exfoliation of large quantities of graphene and other two-dimensional materials, providing a viable route for the industrial scaling of applications based on these layered crystals.

    • James M. Tour
    News & Views
  • Chloroplasts with extended photosynthetic activity beyond the visible absorption spectrum, and living leaves that perform non-biological functions, are made possible by localizing nanoparticles within plant organelles.

    • Gregory D. Scholes
    • Edward H. Sargent
    News & Views
  • Electric fields prompt epithelial cell populations to make coordinated movements such as U-turns.

    • Nir Gov
    News & Views
  • Cracks and defects induced during the transfer of large-area graphene on insulating substrates impair its excellent electronic properties. A defect-free transfer can now be obtained thanks to capillary bridges that anchor the graphene film to the substrate while the underlying growth layer is etched away.

    • Jaime A. Torres
    • Richard B. Kaner
    News & Views
  • In spite of their promise, practical applications of high-temperature cuprate superconductors have been hard to come by. The development of a method to fabricate round wires of the cuprate system Bi-2212 may begin to change this.

    • Joseph V. Minervini
    News & Views
  • The macroscopic alignment of dilute dispersions of graphene oxide can be controlled, with extremely large optical sensitivity, through the application of weak electric fields.

    • Ju Young Kim
    • Sang Ouk Kim
    News & Views