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Cellular mechanotransduction

Sensing rigidity

Nature Materials volume 13, pages 539–540 (2014)Cite this article

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Cells use differences in the binding rates between the extracellular matrix and integrin adhesion receptors to sense matrix rigidity.

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Figure 1: Cells sense matrix rigidity through integrin binding dynamics.

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Authors and Affiliations

  1. José R. García and Andrés J. García are at the Woodruff School of Mechanical Engineering and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, USA,

    José R. García & Andrés J. García

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  1. José R. García
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  2. Andrés J. García
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Correspondence to Andrés J. García.

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García, J., García, A. Sensing rigidity. Nature Mater 13, 539–540 (2014). https://doi.org/10.1038/nmat3996

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