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An intracortical neural prosthetic system developed in animal studies is translated for clinical use in humans with paralysis. Neural control of computer cursor movements achieved with this system represent the highest performance reported to date.
Morgane Rolland and colleagues report that in HIV infection, a higher diversity of infecting founder viruses is associated with markers of poorer clinical outcome.
Lineage tracing shows that, contrary to a recent report, c-kit+ cells take on a vascular endothelial cell fate, not an epithelial one, after lung injury or during normal homeostasis.
A small clinical trial shows that short-term cold acclimation to moderately-cold temperature improves the glucose homeostasis of individuals with type 2 diabetes, without an appreciable activation of their brown adipose tissue.
The study describes the use of integrative approaches to search for candidate therapeutic targets for DIPG, and the identification of an HDAC inhibitor as a potential treatment strategy
Goel et al. report that RIFINs mediate rosetting of Plasmodium falciparum infected erythrocytes in vitro, a phenotype that is associated with severe disease in humans